Detailed information of TA system TA257020

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2723518..2723797
• Replicon: chromosome
• Accession: NZ_CP104020
• Organism: Staphylococcus aureus strain 0831

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: N0J69_RS13575
• Protein ID: WP_001802298.1
• Coordinates: 2723518..2723622 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2723618..2723797 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N0J69_RS13545	2718902..2719684	+	783	WP_000908176.1	ABC transporter ATP-binding protein	-
N0J69_RS13550	2719752..2720609	+	858	WP_000370924.1	HAD family hydrolase	-
N0J69_RS13555	2720841..2721025	-	185	Protein_2633	exotoxin	-
N0J69_RS13560	2721314..2721406	-	93	WP_001790138.1	hypothetical protein	-
N0J69_RS13565	2721695..2722831	+	1137	WP_000115564.1	SAP domain-containing protein	-
N0J69_RS13570	2722874..2723357	+	484	Protein_2636	recombinase family protein	-
N0J69_RS13575	2723518..2723622	+	105	WP_001802298.1	hypothetical protein	Toxin
-	2723618..2723797	-	180	-	-	Antitoxin
N0J69_RS13585	2724122..2725213	-	1092	WP_000495671.1	lytic regulatory protein	-
N0J69_RS13590	2725479..2726459	-	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
N0J69_RS13595	2726461..2726781	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
N0J69_RS13600	2726933..2727598	+	666	WP_001024094.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T257020 WP_001802298.1 NZ_CP104020:2723518-2723622 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT257020 NZ_CP104020:c2723797-2723618 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin