Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2723518..2723781 Replicon chromosome
Accession NZ_CP104020
Organism Staphylococcus aureus strain 0831

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag N0J69_RS13575 Protein ID WP_001802298.1
Coordinates 2723518..2723622 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2723617..2723781 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0J69_RS13545 2718902..2719684 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
N0J69_RS13550 2719752..2720609 + 858 WP_000370924.1 HAD family hydrolase -
N0J69_RS13555 2720841..2721025 - 185 Protein_2633 exotoxin -
N0J69_RS13560 2721314..2721406 - 93 WP_001790138.1 hypothetical protein -
N0J69_RS13565 2721695..2722831 + 1137 WP_000115564.1 SAP domain-containing protein -
N0J69_RS13570 2722874..2723357 + 484 Protein_2636 recombinase family protein -
N0J69_RS13575 2723518..2723622 + 105 WP_001802298.1 hypothetical protein Toxin
- 2723617..2723781 - 165 - - Antitoxin
N0J69_RS13585 2724122..2725213 - 1092 WP_000495671.1 lytic regulatory protein -
N0J69_RS13590 2725479..2726459 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
N0J69_RS13595 2726461..2726781 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
N0J69_RS13600 2726933..2727598 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T257019 WP_001802298.1 NZ_CP104020:2723518-2723622 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT257019 NZ_CP104020:c2723781-2723617 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References