257017

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2433485..2433669 Replicon chromosome
Accession NZ_CP104020
Organism Staphylococcus aureus strain 0831

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag N0J69_RS12050 Protein ID WP_000482650.1
Coordinates 2433485..2433592 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2433609..2433669 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0J69_RS12025 2428847..2429320 + 474 WP_000456489.1 GyrI-like domain-containing protein -
N0J69_RS12030 2429443..2430654 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
N0J69_RS12035 2430836..2431495 - 660 WP_000831298.1 membrane protein -
N0J69_RS12040 2431555..2432697 - 1143 WP_001176863.1 glycerate kinase -
N0J69_RS12045 2432965..2433351 + 387 WP_000779358.1 flippase GtxA -
N0J69_RS12050 2433485..2433592 + 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2433609..2433669 - 61 - - Antitoxin
N0J69_RS12055 2434220..2435983 + 1764 WP_001064838.1 ABC transporter ATP-binding protein -
N0J69_RS12060 2436008..2437741 + 1734 WP_000486494.1 ABC transporter ATP-binding protein -
N0J69_RS12065 2437972..2438139 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T257017 WP_000482650.1 NZ_CP104020:2433485-2433592 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT257017 NZ_CP104020:c2433669-2433609 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References