Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3962867..3963582 Replicon chromosome
Accession NZ_CP103872
Organism Herbaspirillum huttiense strain ZXN111

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NY669_RS17710 Protein ID WP_259435300.1
Coordinates 3963184..3963582 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NY669_RS17705 Protein ID WP_034329811.1
Coordinates 3962867..3963187 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY669_RS17685 (NY669_17685) 3959044..3959706 - 663 WP_259432797.1 response regulator transcription factor -
NY669_RS17690 (NY669_17690) 3959703..3960905 - 1203 WP_259432798.1 PAS domain-containing sensor histidine kinase -
NY669_RS17695 (NY669_17695) 3960961..3961722 - 762 WP_209534462.1 glucose 1-dehydrogenase -
NY669_RS17700 (NY669_17700) 3961944..3962663 - 720 WP_034329812.1 FadR/GntR family transcriptional regulator -
NY669_RS17705 (NY669_17705) 3962867..3963187 - 321 WP_034329811.1 transcriptional regulator Antitoxin
NY669_RS17710 (NY669_17710) 3963184..3963582 - 399 WP_259435300.1 toxin Toxin
NY669_RS17715 (NY669_17715) 3963582..3964910 - 1329 WP_121045052.1 MFS transporter -
NY669_RS17720 (NY669_17720) 3965000..3966202 - 1203 WP_134222985.1 M20 aminoacylase family protein -
NY669_RS17725 (NY669_17725) 3966539..3967519 + 981 WP_259432799.1 LysR family transcriptional regulator -
NY669_RS17730 (NY669_17730) 3967576..3968481 + 906 WP_259432800.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3950552..3978857 28305


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-89)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15635.92 Da        Isoelectric Point: 9.5617

>T256880 WP_259435300.1 NZ_CP103872:c3963582-3963184 [Herbaspirillum huttiense]
MLHYGTMANYTRDAYGSRMEAIFKETRMFAAVRENYLSYDDFATLQQMLMRQPQAGSLIKDAGGLRKIRFPDARRCKGKR
GGLRVIYYFWDEQCHFWLCSIYDKDEMNDLTAHQRKLLRRALEDELSSRKTS

Download         Length: 399 bp

>T256880 NZ_CP103872:c3963582-3963184 [Herbaspirillum huttiense]
ATGCTGCACTATGGTACGATGGCGAACTATACGCGAGATGCGTATGGTTCGCGGATGGAAGCGATCTTCAAAGAAACGCG
AATGTTTGCAGCAGTCCGGGAGAACTACCTCTCGTACGATGACTTTGCAACGCTTCAGCAGATGCTGATGCGACAGCCGC
AAGCGGGAAGCCTCATCAAGGATGCGGGGGGACTTCGAAAGATTCGTTTTCCTGATGCGCGTCGTTGCAAGGGAAAACGT
GGTGGCCTGAGAGTGATCTACTATTTTTGGGACGAACAATGCCACTTCTGGCTTTGCTCTATCTACGACAAAGATGAGAT
GAACGACCTCACCGCTCATCAGAGAAAACTGCTCAGGCGTGCGCTGGAAGATGAACTGTCCTCAAGGAAGACATCATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11961.89 Da        Isoelectric Point: 10.8930

>AT256880 WP_034329811.1 NZ_CP103872:c3963187-3962867 [Herbaspirillum huttiense]
MKKRNLFEELMAGVQDMADEREGKLTLRTSKVKLSPEPVTITAEEIQRVRGKARVSQAIMARSLRVNPRTYQNWEQGVSR
PNAQAAVLLKLVDQDPTLFARISALV

Download         Length: 321 bp

>AT256880 NZ_CP103872:c3963187-3962867 [Herbaspirillum huttiense]
ATGAAAAAAAGAAACTTATTCGAAGAGCTGATGGCGGGCGTGCAAGACATGGCCGATGAGCGAGAGGGCAAGCTGACCTT
GCGCACAAGCAAAGTCAAGCTATCGCCGGAGCCGGTCACGATCACAGCCGAGGAGATTCAACGGGTACGTGGCAAGGCTC
GGGTGTCGCAGGCGATCATGGCCCGCAGCCTGCGTGTCAATCCGCGGACGTATCAAAACTGGGAGCAGGGCGTATCACGG
CCCAACGCGCAGGCAGCCGTGTTGCTCAAGCTGGTGGACCAAGACCCCACGCTCTTCGCACGGATCAGCGCATTGGTGTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References