256877

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2458804..2459412 Replicon chromosome
Accession NZ_CP103872
Organism Herbaspirillum huttiense strain ZXN111

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag NY669_RS11110 Protein ID WP_259434955.1
Coordinates 2459125..2459412 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NY669_RS11105 Protein ID WP_209580605.1
Coordinates 2458804..2459115 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY669_RS11090 (NY669_11090) 2454698..2455897 + 1200 WP_034335527.1 HDOD domain-containing protein -
NY669_RS11095 (NY669_11095) 2455903..2457975 + 2073 WP_259435274.1 EAL domain-containing protein -
NY669_RS11100 (NY669_11100) 2458235..2458771 + 537 WP_034335522.1 superoxide dismutase family protein -
NY669_RS11105 (NY669_11105) 2458804..2459115 - 312 WP_209580605.1 HigA family addiction module antitoxin Antitoxin
NY669_RS11110 (NY669_11110) 2459125..2459412 - 288 WP_259434955.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NY669_RS11120 (NY669_11120) 2459872..2461125 - 1254 WP_259434956.1 aspartate kinase -
NY669_RS11125 (NY669_11125) 2461655..2461933 - 279 WP_034329281.1 DUF4148 domain-containing protein -
NY669_RS11130 (NY669_11130) 2462183..2463094 + 912 WP_259434957.1 LysR family transcriptional regulator -
NY669_RS11135 (NY669_11135) 2463132..2463560 - 429 WP_034329278.1 thioredoxin family protein -
NY669_RS11140 (NY669_11140) 2463672..2464391 + 720 WP_259434958.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(23-95)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-100)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10769.36 Da        Isoelectric Point: 9.3928

>T256877 WP_259434955.1 NZ_CP103872:c2459412-2459125 [Herbaspirillum huttiense]
MILSFRCADTEALFHGKSVPRFANIRAAAERKLQMLDAAATLEFLRTPPGNRLESLHGNRDGQHSIRINGQFRLCFIWHS
IGRIGASHVEIIDYH

Download         Length: 288 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11525.20 Da        Isoelectric Point: 8.8105

>AT256877 WP_209580605.1 NZ_CP103872:c2459115-2458804 [Herbaspirillum huttiense]
MSPAGNRMRPIHPGEILREEFLAPINLSANALAIALHVPATRIGEIVNERRGISPDTALRLARFFGGDAQSWLNLQMTYD
LKIAQRDHGARIEQEVRPLERTS

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References