Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 1043597..1043925 Replicon chromosome
Accession NZ_CP103863
Organism Enterococcus faecalis strain SJ82

Toxin (Protein)


Gene name txpA Uniprot ID A0A3N3Z2N6
Locus tag NYR15_RS05125 Protein ID WP_073340360.1
Coordinates 1043597..1043737 (+) Length 47 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 1043670..1043925 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR15_RS05105 1038811..1039803 + 993 WP_002354765.1 biotin--[acetyl-CoA-carboxylase] ligase -
NYR15_RS05110 1040067..1040696 - 630 WP_002354763.1 lytic polysaccharide monooxygenase -
NYR15_RS05115 1041389..1043005 + 1617 WP_104681241.1 phosphatase PAP2/LCP family protein -
NYR15_RS05120 1043335..1043478 + 144 WP_002392818.1 type I toxin-antitoxin system toxin PepG1 -
NYR15_RS05125 1043597..1043737 + 141 WP_073340360.1 putative holin-like toxin Toxin
- 1043670..1043925 - 256 - - Antitoxin
NYR15_RS05130 1043928..1046924 - 2997 WP_002385134.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-46)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5218.33 Da        Isoelectric Point: 10.3265

>T256840 WP_073340360.1 NZ_CP103863:1043597-1043737 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 141 bp

Antitoxin


Download         Length: 256 bp

>AT256840 NZ_CP103863:c1043925-1043670 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTACAAT
GGTAATGAAAAGAGAGCTATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCTTTTTGATTATTTAA
AAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTGCAATCAAAGCA
ATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N3Z2N6

Antitoxin

Download structure file

References