Detailed information of TA system TA256832

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 892963..893222
• Replicon: chromosome
• Accession: NZ_CP103863
• Organism: Enterococcus faecalis strain SJ82

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: NYR15_RS04440
• Protein ID: WP_075551663.1
• Coordinates: 893121..893222 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	892963..893172 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NYR15_RS04410	888213..889166	-	954	WP_002354964.1	siderophore ABC transporter substrate-binding protein	-
NYR15_RS04415	889205..889960	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
NYR15_RS04420	889957..890922	-	966	WP_002354961.1	iron chelate uptake ABC transporter family permease subunit	-
NYR15_RS04425	890919..891866	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
NYR15_RS04430	892051..892503	+	453	WP_002354958.1	YueI family protein	-
NYR15_RS04435	892688..892789	-	102	WP_075551663.1	putative holin-like toxin	-
-	892963..893172	+	210	-	-	Antitoxin
NYR15_RS04440	893121..893222	-	102	WP_075551663.1	putative holin-like toxin	Toxin
NYR15_RS04445	893412..895682	-	2271	WP_002392683.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
NYR15_RS04450	895853..896353	+	501	WP_002354954.1	cysteine hydrolase family protein	-
NYR15_RS04455	896900..897796	+	897	WP_002354953.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T256832 WP_075551663.1 NZ_CP103863:c893222-893121 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT256832 NZ_CP103863:892963-893172 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin