Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 777500..777763 Replicon chromosome
Accession NZ_CP103860
Organism Staphylococcus aureus strain R3-8

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NYR13_RS03825 Protein ID WP_001802298.1
Coordinates 777500..777604 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 777599..777763 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR13_RS03795 772884..773666 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
NYR13_RS03800 773734..774591 + 858 WP_000370924.1 HAD family hydrolase -
NYR13_RS03805 774823..775007 - 185 Protein_749 exotoxin -
NYR13_RS03810 775296..775388 - 93 WP_001790138.1 hypothetical protein -
NYR13_RS03815 775677..776813 + 1137 WP_000115564.1 SAP domain-containing protein -
NYR13_RS03820 776856..777339 + 484 Protein_752 recombinase family protein -
NYR13_RS03825 777500..777604 + 105 WP_001802298.1 hypothetical protein Toxin
- 777599..777763 - 165 - - Antitoxin
NYR13_RS03835 778104..779195 - 1092 WP_000495671.1 lytic regulatory protein -
NYR13_RS03840 779461..780441 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NYR13_RS03845 780443..780763 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NYR13_RS03850 780915..781580 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T256815 WP_001802298.1 NZ_CP103860:777500-777604 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT256815 NZ_CP103860:c777763-777599 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References