Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | prlF-yhaV (relBE)/YhaV-PrlF |
| Location | 1804961..1805802 | Replicon | chromosome |
| Accession | NZ_CP103851 | ||
| Organism | Ralstonia pseudosolanacearum strain LMG 9673 | ||
Toxin (Protein)
| Gene name | yhaV | Uniprot ID | - |
| Locus tag | NY025_RS07435 | Protein ID | WP_197366231.1 |
| Coordinates | 1804961..1805476 (-) | Length | 172 a.a. |
Antitoxin (Protein)
| Gene name | prlF | Uniprot ID | - |
| Locus tag | NY025_RS07440 | Protein ID | WP_193028732.1 |
| Coordinates | 1805473..1805802 (-) | Length | 110 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NY025_RS07420 (NY025_07420) | 1801063..1801959 | - | 897 | WP_043899999.1 | LysR substrate-binding domain-containing protein | - |
| NY025_RS07425 (NY025_07425) | 1802092..1803373 | - | 1282 | Protein_1475 | IS4 family transposase | - |
| NY025_RS07430 (NY025_07430) | 1803452..1804438 | + | 987 | WP_259421923.1 | IS630 family transposase | - |
| NY025_RS07435 (NY025_07435) | 1804961..1805476 | - | 516 | WP_197366231.1 | type II toxin-antitoxin system YhaV family toxin | Toxin |
| NY025_RS07440 (NY025_07440) | 1805473..1805802 | - | 330 | WP_193028732.1 | type II toxin-antitoxin system PrlF family antitoxin | Antitoxin |
| NY025_RS07450 (NY025_07450) | 1806942..1807148 | + | 207 | Protein_1480 | JAB domain-containing protein | - |
| NY025_RS07455 (NY025_07455) | 1807207..1808388 | + | 1182 | WP_193028729.1 | PDDEXK nuclease domain-containing protein | - |
| NY025_RS07460 (NY025_07460) | 1808543..1809403 | - | 861 | WP_197366230.1 | spermidine synthase | - |
| NY025_RS07465 (NY025_07465) | 1809707..1810642 | + | 936 | WP_193037658.1 | 5-dehydro-4-deoxyglucarate dehydratase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 1803452..1804438 | 986 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 172 a.a. Molecular weight: 19671.40 Da Isoelectric Point: 9.6724
>T256800 WP_197366231.1 NZ_CP103851:c1805476-1804961 [Ralstonia pseudosolanacearum]
MTAVQPVPLVIHGWTIFAHPLLLDQLDALTRQVEAQREKDPTGYVKKNATKRLAAICKLAFDVIPQDPARPEYRQGHTLG
DENKHWFRAKFFQQYRLFFRFHAPSKMIVLAWINDADTKRAYESDDDAYRVFKRMLASGHPPNDWEPLLTEASRQSERLQ
STAGALGTGHR
MTAVQPVPLVIHGWTIFAHPLLLDQLDALTRQVEAQREKDPTGYVKKNATKRLAAICKLAFDVIPQDPARPEYRQGHTLG
DENKHWFRAKFFQQYRLFFRFHAPSKMIVLAWINDADTKRAYESDDDAYRVFKRMLASGHPPNDWEPLLTEASRQSERLQ
STAGALGTGHR
Download Length: 516 bp
Antitoxin
Download Length: 110 a.a. Molecular weight: 12110.59 Da Isoelectric Point: 4.4731
>AT256800 WP_193028732.1 NZ_CP103851:c1805802-1805473 [Ralstonia pseudosolanacearum]
MPVTLEAESTLTDRYQTTVPETVRRALRLGKRDKIHYTIRQTGEVVLTRADDDEAADPVLGQFLRFLAQDIAAHPERLQG
LDTSLVQRIHTLVGGIEVDLDAALSADDE
MPVTLEAESTLTDRYQTTVPETVRRALRLGKRDKIHYTIRQTGEVVLTRADDDEAADPVLGQFLRFLAQDIAAHPERLQG
LDTSLVQRIHTLVGGIEVDLDAALSADDE
Download Length: 330 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|