Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2233405..2233622 Replicon chromosome
Accession NZ_CP103850
Organism Staphylococcus aureus strain NRL 02/947

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NYF25_RS11165 Protein ID WP_001802298.1
Coordinates 2233518..2233622 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2233405..2233460 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF25_RS11140 2229542..2230207 - 666 WP_001024094.1 SDR family oxidoreductase -
NYF25_RS11145 2230359..2230679 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NYF25_RS11150 2230681..2231661 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NYF25_RS11155 2231927..2233018 + 1092 WP_000495671.1 lytic regulatory protein -
- 2233405..2233460 + 56 - - Antitoxin
NYF25_RS11165 2233518..2233622 - 105 WP_001802298.1 hypothetical protein Toxin
NYF25_RS11170 2233783..2234266 - 484 Protein_2158 recombinase family protein -
NYF25_RS11175 2234309..2235445 - 1137 WP_000115564.1 SAP domain-containing protein -
NYF25_RS11180 2235734..2235826 + 93 WP_001790138.1 hypothetical protein -
NYF25_RS11190 2236531..2237388 - 858 WP_000370924.1 HAD family hydrolase -
NYF25_RS11195 2237456..2238238 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T256795 WP_001802298.1 NZ_CP103850:c2233622-2233518 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT256795 NZ_CP103850:2233405-2233460 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References