Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
| Location | 1878039..1879387 | Replicon | chromosome |
| Accession | NZ_CP103834 | ||
| Organism | Actinobacillus genomosp. | ||
Toxin (Protein)
| Gene name | HipT | Uniprot ID | - |
| Locus tag | NYR63_RS08710 | Protein ID | WP_279457171.1 |
| Coordinates | 1878356..1879387 (+) | Length | 344 a.a. |
Antitoxin (Protein)
| Gene name | HipS | Uniprot ID | - |
| Locus tag | NYR63_RS08705 | Protein ID | WP_279457170.1 |
| Coordinates | 1878039..1878356 (+) | Length | 106 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NYR63_RS08685 (NYR63_08680) | 1875685..1876560 | - | 876 | WP_279457166.1 | OmpA family protein | - |
| NYR63_RS08690 (NYR63_08685) | 1876833..1877162 | - | 330 | WP_279457167.1 | SMR family transporter | - |
| NYR63_RS08695 (NYR63_08690) | 1877249..1877539 | - | 291 | WP_279457168.1 | YfcZ/YiiS family protein | - |
| NYR63_RS08700 (NYR63_08695) | 1877743..1878051 | + | 309 | WP_279457169.1 | helix-turn-helix transcriptional regulator | - |
| NYR63_RS08705 (NYR63_08700) | 1878039..1878356 | + | 318 | WP_279457170.1 | HipA N-terminal domain-containing protein | Antitoxin |
| NYR63_RS08710 (NYR63_08705) | 1878356..1879387 | + | 1032 | WP_279457171.1 | HipA domain-containing protein | Toxin |
| NYR63_RS08715 (NYR63_08710) | 1879434..1880066 | - | 633 | WP_279457172.1 | tellurite resistance TerB family protein | - |
| NYR63_RS08720 (NYR63_08715) | 1880207..1880491 | - | 285 | WP_279457173.1 | putative quinol monooxygenase | - |
| NYR63_RS08725 (NYR63_08720) | 1880513..1881325 | - | 813 | WP_279458548.1 | urease accessory protein UreD | - |
| NYR63_RS08730 (NYR63_08725) | 1881510..1882145 | - | 636 | WP_005613192.1 | urease accessory protein UreG | - |
| NYR63_RS08735 (NYR63_08730) | 1882166..1882849 | - | 684 | WP_279458549.1 | urease accessory protein UreF | - |
| NYR63_RS08740 (NYR63_08735) | 1882861..1883424 | - | 564 | WP_279457174.1 | urease accessory protein UreE | - |
| NYR63_RS08745 (NYR63_08740) | 1883547..1884164 | - | 618 | WP_279457175.1 | glutathione S-transferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 344 a.a. Molecular weight: 39306.93 Da Isoelectric Point: 6.4176
>T256785 WP_279457171.1 NZ_CP103834:1878356-1879387 [Actinobacillus genomosp. 1]
MQNCKVLLTPLTDTEQKSGYSQKGLLYLTGQADFIPVLPFNRQGFSTLEPRKQQGMSISGYQPKIQLVIHEKQFQSIAQQ
GTYILKPSPEDYPFLAENEHATMQLMAKLGFIVPENGLIPFQATSEQTEYAFVIKRFDRTNDNKPIHQEQLDGAMSITEK
YGKTGSDNEQYISYEQAVKFILQHTENNLAQQQELFRRIVYAYLLGNNDLHLRNFSLIYSKTGEAKLAPIYDYVSVVPYK
AIFEGTILALPLLAKEEGNKELAHGFTTQYGEYIGQDFIEFGENIGLNRNVILKKLLPQILKEKTIVESVYQHSFMSLAH
QELVLKNYHRRLQLLQIIDEPSL
MQNCKVLLTPLTDTEQKSGYSQKGLLYLTGQADFIPVLPFNRQGFSTLEPRKQQGMSISGYQPKIQLVIHEKQFQSIAQQ
GTYILKPSPEDYPFLAENEHATMQLMAKLGFIVPENGLIPFQATSEQTEYAFVIKRFDRTNDNKPIHQEQLDGAMSITEK
YGKTGSDNEQYISYEQAVKFILQHTENNLAQQQELFRRIVYAYLLGNNDLHLRNFSLIYSKTGEAKLAPIYDYVSVVPYK
AIFEGTILALPLLAKEEGNKELAHGFTTQYGEYIGQDFIEFGENIGLNRNVILKKLLPQILKEKTIVESVYQHSFMSLAH
QELVLKNYHRRLQLLQIIDEPSL
Download Length: 1032 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|