256759

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2030066..2031414 Replicon chromosome
Accession NZ_CP103827
Organism Actinobacillus equuli subsp. haemolyticus strain 3090

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag NYR82_RS09535 Protein ID WP_279437033.1
Coordinates 2030066..2031097 (-) Length 344 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag NYR82_RS09540 Protein ID WP_279437034.1
Coordinates 2031097..2031414 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR82_RS09500 (NYR82_09505) 2025462..2026145 + 684 WP_279442800.1 urease accessory protein UreF -
NYR82_RS09505 (NYR82_09510) 2026157..2026633 + 477 WP_279441880.1 PIN domain-containing protein -
NYR82_RS09510 (NYR82_09515) 2026675..2027286 + 612 WP_279441881.1 hypothetical protein -
NYR82_RS09515 (NYR82_09520) 2027301..2027936 + 636 WP_279441882.1 urease accessory protein UreG -
NYR82_RS09520 (NYR82_09525) 2028103..2028915 + 813 WP_279441883.1 urease accessory protein UreD -
NYR82_RS09525 (NYR82_09530) 2028937..2029221 + 285 WP_279441884.1 putative quinol monooxygenase -
NYR82_RS09530 (NYR82_09535) 2029388..2030020 + 633 WP_279441885.1 tellurite resistance TerB family protein -
NYR82_RS09535 (NYR82_09540) 2030066..2031097 - 1032 WP_279437033.1 HipA domain-containing protein Toxin
NYR82_RS09540 (NYR82_09545) 2031097..2031414 - 318 WP_279437034.1 HipA N-terminal domain-containing protein Antitoxin
NYR82_RS09545 (NYR82_09550) 2031402..2031710 - 309 WP_279437035.1 helix-turn-helix transcriptional regulator -
NYR82_RS09550 (NYR82_09555) 2031913..2032203 + 291 WP_005602339.1 YfcZ/YiiS family protein -
NYR82_RS09555 (NYR82_09560) 2032291..2032620 + 330 WP_279441886.1 SMR family transporter -
NYR82_RS09560 (NYR82_09565) 2032699..2033193 - 495 WP_279441887.1 hemerythrin domain-containing protein -
NYR82_RS09565 (NYR82_09570) 2033358..2034284 - 927 WP_015674211.1 ADP-glyceromanno-heptose 6-epimerase -
NYR82_RS09570 (NYR82_09575) 2034424..2034936 - 513 WP_039195517.1 peptide deformylase -
NYR82_RS09575 (NYR82_09580) 2035121..2036274 + 1154 Protein_1851 DNA-processing protein DprA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(56-290)

Antitoxin

HipA, N-terminal subdomain 1

(9-101)


Sequences

Toxin        


Download         Length: 344 a.a.        Molecular weight: 39591.22 Da        Isoelectric Point: 6.3975

>T256759 WP_279437033.1 NZ_CP103827:c2031097-2030066 [Actinobacillus equuli subsp. haemolyticus]
MQNCRVLLTQLTDTEQKSGYSQKGLYYLTGQSDFIPVLPFNRQDFSTLEPRKQQGMSISGYQPKLQLVIHEKQFQSIAQQ
GNYILKPSPEDYPFLAENEHATMQLMAKLGFVVPENGLIPFQSVSEQMEYAFVIKRFDRTNDNKSIHQEQLDGAMNVTEK
YGKTGSDNEQYISYEQAVKFILQHTENNLAQQQELFRRIVYAYLLGNNDLHLRNFSLVYSKTGEANLAPVYDYVSVVPYK
AIFEGTILALPLLVKEEGNKELAHGFTTKYGEYIGQDFIEFGENIGLNRKVILKKLLPQILKEKTIVESVYQRSFMPLEH
QALVLKNYYRRLQLLQILDEPSL

Download         Length: 1032 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12291.10 Da        Isoelectric Point: 4.8047

>AT256759 WP_279437034.1 NZ_CP103827:c2031414-2031097 [Actinobacillus equuli subsp. haemolyticus]
MRSIKRSAKVFLYDEPVGYLYQDEMGFHFSYFKDYIGMPLSLSLPVVQQDFHSEQLFPYFASLIPEGWLKAKYNVLQKID
EQDQFGLLLNNGENMLGAITIKREE

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References