Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 2069803..2071151 | Replicon | chromosome |
Accession | NZ_CP103814 | ||
Organism | Actinobacillus equuli subsp. haemolyticus strain 4091 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | NYR68_RS09660 | Protein ID | WP_279622219.1 |
Coordinates | 2069803..2070834 (-) | Length | 344 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | - |
Locus tag | NYR68_RS09665 | Protein ID | WP_279622220.1 |
Coordinates | 2070834..2071151 (-) | Length | 106 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NYR68_RS09625 (NYR68_09630) | 2065035..2065652 | + | 618 | WP_279455884.1 | glutathione S-transferase | - |
NYR68_RS09630 (NYR68_09635) | 2065725..2066288 | + | 564 | WP_279440749.1 | urease accessory protein UreE | - |
NYR68_RS09635 (NYR68_09640) | 2066300..2066983 | + | 684 | WP_164997545.1 | urease accessory protein UreF | - |
NYR68_RS09640 (NYR68_09645) | 2067004..2067639 | + | 636 | WP_005613192.1 | urease accessory protein UreG | - |
NYR68_RS09645 (NYR68_09650) | 2067824..2068636 | + | 813 | WP_279622827.1 | urease accessory protein UreD | - |
NYR68_RS09650 (NYR68_09655) | 2068658..2068948 | + | 291 | WP_279622218.1 | putative quinol monooxygenase | - |
NYR68_RS09655 (NYR68_09660) | 2069125..2069757 | + | 633 | WP_278226403.1 | tellurite resistance TerB family protein | - |
NYR68_RS09660 (NYR68_09665) | 2069803..2070834 | - | 1032 | WP_279622219.1 | HipA domain-containing protein | Toxin |
NYR68_RS09665 (NYR68_09670) | 2070834..2071151 | - | 318 | WP_279622220.1 | HipA N-terminal domain-containing protein | Antitoxin |
NYR68_RS09670 (NYR68_09675) | 2071139..2071447 | - | 309 | WP_279622221.1 | helix-turn-helix transcriptional regulator | - |
NYR68_RS09675 (NYR68_09680) | 2071650..2071940 | + | 291 | WP_279622222.1 | YfcZ/YiiS family protein | - |
NYR68_RS09680 (NYR68_09685) | 2072028..2072357 | + | 330 | WP_279455885.1 | SMR family transporter | - |
NYR68_RS09685 (NYR68_09690) | 2072425..2072919 | - | 495 | WP_279471695.1 | hemerythrin domain-containing protein | - |
NYR68_RS09690 (NYR68_09695) | 2073084..2074010 | - | 927 | WP_015674211.1 | ADP-glyceromanno-heptose 6-epimerase | - |
NYR68_RS09695 (NYR68_09700) | 2074151..2074663 | - | 513 | WP_039195517.1 | peptide deformylase | - |
NYR68_RS09700 (NYR68_09705) | 2074848..2076002 | + | 1155 | WP_279622223.1 | DNA-processing protein DprA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 344 a.a. Molecular weight: 39607.22 Da Isoelectric Point: 6.6170
>T256714 WP_279622219.1 NZ_CP103814:c2070834-2069803 [Actinobacillus equuli subsp. haemolyticus]
MQNCRVLLTQLTDTEQKSGYSQKGLYYLTGRSDFIPVLPFNRQDFSTLEPRKQQGMSISGYQPKLQLVIHEKQFQSIAQQ
GNYILKPSPEDYPFLAENEHATMQLMAKLGFVVPENGLIPFQSSSEQTEYAFVIKRFDRTNDNKSIHQEQLDGAMNVMEK
YGKTGSDNEQYISYEQAVKFILQHTENNLAQQQELFRRIVYAYLLGNNDLHLRNFSLVYSKTGEANLAPVYDYVSVVPYK
AIFEGTILALPLLVKEEGNKELAHGFTTKYGEYIGQDFIEFGENIGLNRKVILKKLLPQILKEKTIVESVYQRSFMPLEH
QALVLKNYYRRLQLLQILDEPSL
MQNCRVLLTQLTDTEQKSGYSQKGLYYLTGRSDFIPVLPFNRQDFSTLEPRKQQGMSISGYQPKLQLVIHEKQFQSIAQQ
GNYILKPSPEDYPFLAENEHATMQLMAKLGFVVPENGLIPFQSSSEQTEYAFVIKRFDRTNDNKSIHQEQLDGAMNVMEK
YGKTGSDNEQYISYEQAVKFILQHTENNLAQQQELFRRIVYAYLLGNNDLHLRNFSLVYSKTGEANLAPVYDYVSVVPYK
AIFEGTILALPLLVKEEGNKELAHGFTTKYGEYIGQDFIEFGENIGLNRKVILKKLLPQILKEKTIVESVYQRSFMPLEH
QALVLKNYYRRLQLLQILDEPSL
Download Length: 1032 bp
Antitoxin
Download Length: 106 a.a. Molecular weight: 12239.02 Da Isoelectric Point: 6.4796
>AT256714 WP_279622220.1 NZ_CP103814:c2071151-2070834 [Actinobacillus equuli subsp. haemolyticus]
MRNIKRSAQVFLYDEPVGQIYQDDMGFHFSYFKDYVGIPLSLSLPVAQQHFHSEQLFPYFASLIPEGWLKAKYNVLQKID
EQDHFGLLLNNGENMLGAITIKREK
MRNIKRSAQVFLYDEPVGQIYQDDMGFHFSYFKDYVGIPLSLSLPVAQQHFHSEQLFPYFASLIPEGWLKAKYNVLQKID
EQDHFGLLLNNGENMLGAITIKREK
Download Length: 318 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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