Detailed information of TA system TA256645

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2069341..2069587
• Replicon: chromosome
• Accession: NZ_CP103783
• Organism: Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: NYR92_RS10370
• Protein ID: WP_109789044.1
• Coordinates: 2069341..2069433 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2069414..2069587 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NYR92_RS10355	2064500..2064835	+	336	WP_009967409.1	hypothetical protein	-
NYR92_RS10360	2064882..2068487	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
NYR92_RS10365	2068720..2069052	-	333	WP_026009814.1	hypothetical protein	-
NYR92_RS10370	2069341..2069433	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2069414..2069587	-	174	-	-	Antitoxin
NYR92_RS10375	2069702..2070544	-	843	WP_003231327.1	hypothetical protein	-
NYR92_RS10380	2070744..2071202	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
NYR92_RS10385	2071212..2073014	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
NYR92_RS10390	2073116..2073673	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2002859..2099249	96390
	-	inside	Prophage	-	-	2055326..2081205	25879

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T256645 WP_109789044.1 NZ_CP103783:2069341-2069433 [Bacillus subtilis subsp. subtilis str. 168]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT256645 NZ_CP103783:c2069587-2069414 [Bacillus subtilis subsp. subtilis str. 168]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin