Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 689540..690233 Replicon chromosome
Accession NZ_CP103758
Organism Escherichia coli strain p10B

Toxin (Protein)


Gene name mqsR Uniprot ID U9ZN09
Locus tag NYO15_RS03380 Protein ID WP_000415585.1
Coordinates 689540..689836 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID S1EBV2
Locus tag NYO15_RS03385 Protein ID WP_000650107.1
Coordinates 689838..690233 (+) Length 132 a.a.

Genomic Context


NYO15_RS03345NYO15_RS03350NYO15_RS03355NYO15_RS03370NYO15_RS03375NYO15_RS03380NYO15_RS03385NYO15_RS03390NYO15_RS03395NYO15_RS03360NYO15_RS03365
Location: 684674..685153 (480 bp)
Type: Others
Protein ID: WP_000065332.1
Location: 685156..685866 (711 bp)
Type: Others
Protein ID: WP_000834030.1
Location: 685873..686205 (333 bp)
Type: Others
Protein ID: WP_000914690.1
Location: 688408..688800 (393 bp)
Type: Others
Protein ID: WP_000712658.1
Location: 688853..689335 (483 bp)
Type: Others
Protein ID: WP_000183505.1
Location: 689540..689836 (297 bp)
Type: Toxin
Protein ID: WP_000415585.1
Location: 689838..690233 (396 bp)
Type: Antitoxin
Protein ID: WP_000650107.1
Location: 690366..691973 (1608 bp)
Type: Others
Protein ID: WP_001375094.1
Location: 692111..694369 (2259 bp)
Type: Others
Protein ID: WP_001281841.1
Location: 686251..687600 (1350 bp)
Type: Others
Protein ID: WP_000673358.1
Location: 687597..688256 (660 bp)
Type: Others
Protein ID: WP_001221502.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NYO15_RS03345 (684674)684674..685153+480WP_000065332.1Hcp family type VI secretion system effector-
NYO15_RS03350 (685156)685156..685866+711WP_000834030.1hypothetical protein-
NYO15_RS03355 (685873)685873..686205+333WP_000914690.1DUF2645 family protein-
NYO15_RS03360 (686251)686251..687600-1350WP_000673358.1quorum sensing histidine kinase QseC-
NYO15_RS03365 (687597)687597..688256-660WP_001221502.1quorum sensing response regulator transcription factor QseB-
NYO15_RS03370 (688408)688408..688800+393WP_000712658.1OB fold stress tolerance protein YgiW-
NYO15_RS03375 (688853)688853..689335+483WP_000183505.1GyrI-like domain-containing protein-
NYO15_RS03380 (689540)689540..689836+297WP_000415585.1type II toxin-antitoxin system toxin MqsRToxin
NYO15_RS03385 (689838)689838..690233+396WP_000650107.1type II toxin-antitoxin system antitoxin MqsAAntitoxin
NYO15_RS03390 (690366)690366..691973+1608WP_001375094.1ABC transporter substrate-binding protein-
NYO15_RS03395 (692111)692111..694369+2259WP_001281841.1DNA topoisomerase IV subunit A-

Associated MGEs


Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-97)

Antitoxin

(3-47)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11261.99 Da        Isoelectric Point: 8.9070

>T256560 WP_000415585.1 NZ_CP103758:689540-689836 [Escherichia coli]
MEKRTPHTRLSQVKKLVNTGQVRTTRSALLNADELGLDFDGMCNVIIGLSESDFYKSMTTYSDHTIWQDVYRPRLVTGQV
YLKITVIHDVLIVSFKEK

Download         Length: 297 bp


Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14703.10 Da        Isoelectric Point: 9.2136

>AT256560 WP_000650107.1 NZ_CP103758:689838-690233 [Escherichia coli]
MKCPVCHQGEMVSGIKDIPYTFRGRKTVLKGIHGLYCVHCEESIMNKEESDAFMAQVKAFRASVNAETVAPEFIVKVRKK
LSLTQKEASEIFGGGVNAFSRYEKGNAQPHPSTIKLLRVLDKHPELLNEIR

Download         Length: 396 bp


Similar Proteins


Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBU9ZN09


Antitoxin

Loading, please wait
Source
ID
Structure
PDB3HI2
PDB3GA8
PDB3O9X
PDB2KZ8
PDB3FMY
PDB3GN5
AlphaFold DBA0A7U9LU65

References