Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
Location | 3633086..3633627 | Replicon | chromosome |
Accession | NZ_CP103694 | ||
Organism | Escherichia coli strain ST12468 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | U9XPG0 |
Locus tag | M5T31_RS17885 | Protein ID | WP_000615976.1 |
Coordinates | 3633349..3633627 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | S1EWQ0 |
Locus tag | M5T31_RS17880 | Protein ID | WP_000729704.1 |
Coordinates | 3633086..3633346 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M5T31_RS17860 (3628762) | 3628762..3629547 | - | 786 | WP_000207587.1 | putative lateral flagellar export/assembly protein LafU | - |
M5T31_RS17865 (3629492) | 3629492..3631230 | + | 1739 | Protein_3499 | flagellar biosynthesis protein FlhA | - |
M5T31_RS17870 (3631454) | 3631454..3631951 | - | 498 | WP_000006255.1 | REP-associated tyrosine transposase RayT | - |
M5T31_RS17875 (3632127) | 3632127..3632900 | - | 774 | WP_015675129.1 | C40 family peptidase | - |
M5T31_RS17880 (3633086) | 3633086..3633346 | + | 261 | WP_000729704.1 | type II toxin-antitoxin system antitoxin DinJ | Antitoxin |
M5T31_RS17885 (3633349) | 3633349..3633627 | + | 279 | WP_000615976.1 | type II toxin-antitoxin system mRNA interferase toxin YafQ | Toxin |
M5T31_RS17890 (3633783) | 3633783..3634523 | + | 741 | WP_001225679.1 | peptidoglycan meso-diaminopimelic acid protein amidase | - |
M5T31_RS17895 (3634494) | 3634494..3635261 | - | 768 | WP_000333379.1 | class II glutamine amidotransferase | - |
M5T31_RS17900 (3635467) | 3635467..3636045 | - | 579 | WP_000284050.1 | D-sedoheptulose 7-phosphate isomerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | gmhA/lpcA | 3625928..3647045 | 21117 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | U9XPG0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0Y6Z6 |