Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2962525..2963755 Replicon chromosome
Accession NC_015945
Organism Muricauda ruestringensis DSM 13258

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag MURRU_RS13355 Protein ID WP_014034005.1
Coordinates 2962832..2963755 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag MURRU_RS13350 Protein ID WP_041801548.1
Coordinates 2962525..2962839 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MURRU_RS13330 2957594..2960032 + 2439 WP_014034001.1 phosphoenolpyruvate synthase -
MURRU_RS13335 2960220..2961449 + 1230 WP_014034002.1 MFS transporter -
MURRU_RS13340 2961836..2962111 + 276 WP_083816281.1 integrase core domain-containing protein -
MURRU_RS13345 2962310..2962525 + 216 WP_014034003.1 helix-turn-helix transcriptional regulator -
MURRU_RS13350 2962525..2962839 + 315 WP_041801548.1 HipA N-terminal domain-containing protein Antitoxin
MURRU_RS13355 2962832..2963755 + 924 WP_014034005.1 HipA domain-containing protein Toxin
MURRU_RS13360 2964171..2967332 - 3162 WP_014034006.1 hypothetical protein -
MURRU_RS13365 2967329..2968204 - 876 WP_014034007.1 ABC transporter ATP-binding protein -
MURRU_RS13370 2968226..2968429 - 204 WP_014034008.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(52-277)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 35191.80 Da        Isoelectric Point: 9.3528

>T25617 WP_014034005.1 NC_015945:2962832-2963755 [Muricauda ruestringensis DSM 13258]
MNRCPITYELCGTAKYSGRGLKMIAPKLTDLKDLPYSAAELRRESANRAKKLSIQGVQPKLSATVSVVDQEFKIVDQFGT
YIIKPQNDLFPQLPENEDLTMRMAKAYGLNVPFHGMVYAKDGSLSYFIKRFDRYGKGKKYAVEDFAQLTGNTRDTKYRFT
MERVVPVVDEFCSFPVVEKADFFKRIIFCYVTGNEDMHLKNFSLITKNGKTTLAPAYDLLNSTISIKNPEEEIALTLKGK
KSNFIASDFIGYYAKERLQLNDRIIEVILGDMYQATPKWKELIAVSFLSDEMKEKYLNLLESRLKLF

Download         Length: 924 bp

>T25617 NC_015945:2962832-2963755 [Muricauda ruestringensis DSM 13258]
ATGAATAGGTGCCCAATCACATACGAACTGTGCGGTACGGCGAAATACAGTGGGAGAGGACTAAAAATGATTGCACCCAA
ATTAACCGATCTGAAGGATTTACCCTATTCAGCAGCCGAATTGAGACGGGAATCAGCAAATAGGGCCAAGAAACTATCCA
TCCAAGGGGTACAACCTAAATTAAGTGCAACTGTTTCCGTGGTTGACCAGGAATTTAAAATTGTAGATCAATTCGGAACC
TACATCATAAAACCGCAAAATGATTTATTTCCCCAGTTGCCCGAAAATGAGGACCTGACCATGCGCATGGCTAAAGCCTA
TGGCTTGAATGTTCCATTTCATGGGATGGTATATGCCAAGGATGGCAGTCTCTCGTATTTTATAAAACGTTTCGATCGTT
ATGGCAAGGGAAAGAAATACGCTGTGGAGGATTTTGCACAATTAACGGGAAATACGAGGGATACCAAATACCGCTTTACC
ATGGAAAGAGTGGTTCCCGTTGTTGATGAGTTTTGTTCATTTCCCGTTGTTGAAAAGGCTGATTTTTTTAAAAGGATAAT
TTTCTGTTATGTAACTGGAAATGAGGATATGCATTTAAAAAACTTTTCCTTGATTACAAAAAACGGAAAAACCACCTTGG
CACCAGCCTATGATCTATTGAATTCCACAATTTCCATTAAAAATCCAGAAGAAGAAATCGCATTGACCTTAAAAGGAAAA
AAAAGCAATTTCATAGCATCGGATTTTATTGGTTATTATGCGAAAGAGCGATTACAATTGAATGATAGAATAATTGAAGT
GATTCTTGGGGACATGTATCAGGCAACTCCAAAATGGAAGGAGTTGATAGCAGTTTCTTTTCTTTCGGATGAAATGAAAG
AGAAATATCTAAATCTATTGGAGTCGAGATTGAAATTGTTTTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11743.41 Da        Isoelectric Point: 4.6413

>AT25617 WP_041801548.1 NC_015945:2962525-2962839 [Muricauda ruestringensis DSM 13258]
MRKAVVYTHGKRAGVLTEVSPNEYHFDYDEDYDGDSISLTMPVSQKKYSFKSFPPFFEGLLPEGVMLQGLLRIVKIDQKD
YFSQLMATGADLVGAITVKPMEDE

Download         Length: 315 bp

>AT25617 NC_015945:2962525-2962839 [Muricauda ruestringensis DSM 13258]
ATGAGAAAGGCAGTTGTATATACCCATGGCAAAAGAGCAGGAGTACTTACCGAAGTTTCTCCAAATGAATATCATTTTGA
TTATGATGAAGATTATGATGGAGATTCTATCTCATTGACCATGCCAGTAAGCCAGAAAAAATACAGTTTTAAATCATTCC
CCCCCTTTTTTGAAGGTTTGTTGCCTGAGGGTGTAATGTTGCAGGGGCTATTGAGGATTGTAAAAATTGATCAAAAGGAT
TATTTCTCACAATTAATGGCGACAGGTGCTGATCTGGTTGGTGCAATAACCGTAAAACCAATGGAGGATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References