Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 2962525..2963755 | Replicon | chromosome |
Accession | NC_015945 | ||
Organism | Muricauda ruestringensis DSM 13258 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | MURRU_RS13355 | Protein ID | WP_014034005.1 |
Coordinates | 2962832..2963755 (+) | Length | 308 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | - |
Locus tag | MURRU_RS13350 | Protein ID | WP_041801548.1 |
Coordinates | 2962525..2962839 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MURRU_RS13330 | 2957594..2960032 | + | 2439 | WP_014034001.1 | phosphoenolpyruvate synthase | - |
MURRU_RS13335 | 2960220..2961449 | + | 1230 | WP_014034002.1 | MFS transporter | - |
MURRU_RS13340 | 2961836..2962111 | + | 276 | WP_083816281.1 | integrase core domain-containing protein | - |
MURRU_RS13345 | 2962310..2962525 | + | 216 | WP_014034003.1 | helix-turn-helix transcriptional regulator | - |
MURRU_RS13350 | 2962525..2962839 | + | 315 | WP_041801548.1 | HipA N-terminal domain-containing protein | Antitoxin |
MURRU_RS13355 | 2962832..2963755 | + | 924 | WP_014034005.1 | HipA domain-containing protein | Toxin |
MURRU_RS13360 | 2964171..2967332 | - | 3162 | WP_014034006.1 | hypothetical protein | - |
MURRU_RS13365 | 2967329..2968204 | - | 876 | WP_014034007.1 | ABC transporter ATP-binding protein | - |
MURRU_RS13370 | 2968226..2968429 | - | 204 | WP_014034008.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 35191.80 Da Isoelectric Point: 9.3528
>T25617 WP_014034005.1 NC_015945:2962832-2963755 [Muricauda ruestringensis DSM 13258]
MNRCPITYELCGTAKYSGRGLKMIAPKLTDLKDLPYSAAELRRESANRAKKLSIQGVQPKLSATVSVVDQEFKIVDQFGT
YIIKPQNDLFPQLPENEDLTMRMAKAYGLNVPFHGMVYAKDGSLSYFIKRFDRYGKGKKYAVEDFAQLTGNTRDTKYRFT
MERVVPVVDEFCSFPVVEKADFFKRIIFCYVTGNEDMHLKNFSLITKNGKTTLAPAYDLLNSTISIKNPEEEIALTLKGK
KSNFIASDFIGYYAKERLQLNDRIIEVILGDMYQATPKWKELIAVSFLSDEMKEKYLNLLESRLKLF
MNRCPITYELCGTAKYSGRGLKMIAPKLTDLKDLPYSAAELRRESANRAKKLSIQGVQPKLSATVSVVDQEFKIVDQFGT
YIIKPQNDLFPQLPENEDLTMRMAKAYGLNVPFHGMVYAKDGSLSYFIKRFDRYGKGKKYAVEDFAQLTGNTRDTKYRFT
MERVVPVVDEFCSFPVVEKADFFKRIIFCYVTGNEDMHLKNFSLITKNGKTTLAPAYDLLNSTISIKNPEEEIALTLKGK
KSNFIASDFIGYYAKERLQLNDRIIEVILGDMYQATPKWKELIAVSFLSDEMKEKYLNLLESRLKLF
Download Length: 924 bp
>T25617 NC_015945:2962832-2963755 [Muricauda ruestringensis DSM 13258]
ATGAATAGGTGCCCAATCACATACGAACTGTGCGGTACGGCGAAATACAGTGGGAGAGGACTAAAAATGATTGCACCCAA
ATTAACCGATCTGAAGGATTTACCCTATTCAGCAGCCGAATTGAGACGGGAATCAGCAAATAGGGCCAAGAAACTATCCA
TCCAAGGGGTACAACCTAAATTAAGTGCAACTGTTTCCGTGGTTGACCAGGAATTTAAAATTGTAGATCAATTCGGAACC
TACATCATAAAACCGCAAAATGATTTATTTCCCCAGTTGCCCGAAAATGAGGACCTGACCATGCGCATGGCTAAAGCCTA
TGGCTTGAATGTTCCATTTCATGGGATGGTATATGCCAAGGATGGCAGTCTCTCGTATTTTATAAAACGTTTCGATCGTT
ATGGCAAGGGAAAGAAATACGCTGTGGAGGATTTTGCACAATTAACGGGAAATACGAGGGATACCAAATACCGCTTTACC
ATGGAAAGAGTGGTTCCCGTTGTTGATGAGTTTTGTTCATTTCCCGTTGTTGAAAAGGCTGATTTTTTTAAAAGGATAAT
TTTCTGTTATGTAACTGGAAATGAGGATATGCATTTAAAAAACTTTTCCTTGATTACAAAAAACGGAAAAACCACCTTGG
CACCAGCCTATGATCTATTGAATTCCACAATTTCCATTAAAAATCCAGAAGAAGAAATCGCATTGACCTTAAAAGGAAAA
AAAAGCAATTTCATAGCATCGGATTTTATTGGTTATTATGCGAAAGAGCGATTACAATTGAATGATAGAATAATTGAAGT
GATTCTTGGGGACATGTATCAGGCAACTCCAAAATGGAAGGAGTTGATAGCAGTTTCTTTTCTTTCGGATGAAATGAAAG
AGAAATATCTAAATCTATTGGAGTCGAGATTGAAATTGTTTTGA
ATGAATAGGTGCCCAATCACATACGAACTGTGCGGTACGGCGAAATACAGTGGGAGAGGACTAAAAATGATTGCACCCAA
ATTAACCGATCTGAAGGATTTACCCTATTCAGCAGCCGAATTGAGACGGGAATCAGCAAATAGGGCCAAGAAACTATCCA
TCCAAGGGGTACAACCTAAATTAAGTGCAACTGTTTCCGTGGTTGACCAGGAATTTAAAATTGTAGATCAATTCGGAACC
TACATCATAAAACCGCAAAATGATTTATTTCCCCAGTTGCCCGAAAATGAGGACCTGACCATGCGCATGGCTAAAGCCTA
TGGCTTGAATGTTCCATTTCATGGGATGGTATATGCCAAGGATGGCAGTCTCTCGTATTTTATAAAACGTTTCGATCGTT
ATGGCAAGGGAAAGAAATACGCTGTGGAGGATTTTGCACAATTAACGGGAAATACGAGGGATACCAAATACCGCTTTACC
ATGGAAAGAGTGGTTCCCGTTGTTGATGAGTTTTGTTCATTTCCCGTTGTTGAAAAGGCTGATTTTTTTAAAAGGATAAT
TTTCTGTTATGTAACTGGAAATGAGGATATGCATTTAAAAAACTTTTCCTTGATTACAAAAAACGGAAAAACCACCTTGG
CACCAGCCTATGATCTATTGAATTCCACAATTTCCATTAAAAATCCAGAAGAAGAAATCGCATTGACCTTAAAAGGAAAA
AAAAGCAATTTCATAGCATCGGATTTTATTGGTTATTATGCGAAAGAGCGATTACAATTGAATGATAGAATAATTGAAGT
GATTCTTGGGGACATGTATCAGGCAACTCCAAAATGGAAGGAGTTGATAGCAGTTTCTTTTCTTTCGGATGAAATGAAAG
AGAAATATCTAAATCTATTGGAGTCGAGATTGAAATTGTTTTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11743.41 Da Isoelectric Point: 4.6413
>AT25617 WP_041801548.1 NC_015945:2962525-2962839 [Muricauda ruestringensis DSM 13258]
MRKAVVYTHGKRAGVLTEVSPNEYHFDYDEDYDGDSISLTMPVSQKKYSFKSFPPFFEGLLPEGVMLQGLLRIVKIDQKD
YFSQLMATGADLVGAITVKPMEDE
MRKAVVYTHGKRAGVLTEVSPNEYHFDYDEDYDGDSISLTMPVSQKKYSFKSFPPFFEGLLPEGVMLQGLLRIVKIDQKD
YFSQLMATGADLVGAITVKPMEDE
Download Length: 315 bp
>AT25617 NC_015945:2962525-2962839 [Muricauda ruestringensis DSM 13258]
ATGAGAAAGGCAGTTGTATATACCCATGGCAAAAGAGCAGGAGTACTTACCGAAGTTTCTCCAAATGAATATCATTTTGA
TTATGATGAAGATTATGATGGAGATTCTATCTCATTGACCATGCCAGTAAGCCAGAAAAAATACAGTTTTAAATCATTCC
CCCCCTTTTTTGAAGGTTTGTTGCCTGAGGGTGTAATGTTGCAGGGGCTATTGAGGATTGTAAAAATTGATCAAAAGGAT
TATTTCTCACAATTAATGGCGACAGGTGCTGATCTGGTTGGTGCAATAACCGTAAAACCAATGGAGGATGAATAG
ATGAGAAAGGCAGTTGTATATACCCATGGCAAAAGAGCAGGAGTACTTACCGAAGTTTCTCCAAATGAATATCATTTTGA
TTATGATGAAGATTATGATGGAGATTCTATCTCATTGACCATGCCAGTAAGCCAGAAAAAATACAGTTTTAAATCATTCC
CCCCCTTTTTTGAAGGTTTGTTGCCTGAGGGTGTAATGTTGCAGGGGCTATTGAGGATTGTAAAAATTGATCAAAAGGAT
TATTTCTCACAATTAATGGCGACAGGTGCTGATCTGGTTGGTGCAATAACCGTAAAACCAATGGAGGATGAATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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