Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 1893519..1894021 | Replicon | chromosome |
Accession | NZ_CP103559 | ||
Organism | Escherichia coli strain 3059 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | D3GZ85 |
Locus tag | M5T18_RS08930 | Protein ID | WP_000767820.1 |
Coordinates | 1893767..1894021 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | S1Q063 |
Locus tag | M5T18_RS08925 | Protein ID | WP_001259255.1 |
Coordinates | 1893519..1893770 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M5T18_RS08900 (1888696) | 1888696..1889763 | - | 1068 | WP_001403692.1 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | - |
M5T18_RS08905 (1889763) | 1889763..1890833 | - | 1071 | WP_001403691.1 | histidinol-phosphate transaminase | - |
M5T18_RS08910 (1890830) | 1890830..1892134 | - | 1305 | WP_001403690.1 | histidinol dehydrogenase | - |
M5T18_RS08915 (1892140) | 1892140..1893039 | - | 900 | WP_000131782.1 | ATP phosphoribosyltransferase | - |
M5T18_RS08920 (1893185) | 1893185..1893235 | - | 51 | WP_001364200.1 | his operon leader peptide | - |
M5T18_RS08925 (1893519) | 1893519..1893770 | + | 252 | WP_001259255.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
M5T18_RS08930 (1893767) | 1893767..1894021 | + | 255 | WP_000767820.1 | type II toxin-antitoxin system mRNA interferase toxin YoeB | Toxin |
M5T18_RS08935 (1894104) | 1894104..1894928 | + | 825 | WP_000754749.1 | SDR family oxidoreductase | - |
M5T18_RS08940 (1894974) | 1894974..1895903 | + | 930 | WP_000803351.1 | LysR substrate-binding domain-containing protein | - |
M5T18_RS08945 (1896118) | 1896118..1896180 | + | 63 | WP_010723108.1 | membrane protein YoeI | - |
M5T18_RS08950 (1896170) | 1896170..1897528 | + | 1359 | WP_000019197.1 | putrescine/proton symporter PlaP | - |
M5T18_RS08955 (1897707) | 1897707..1898765 | + | 1059 | WP_000492315.1 | thiosulfate utilization transporter TsuA/YeeE | - |
M5T18_RS08960 (1898779) | 1898779..1899006 | + | 228 | WP_000985273.1 | thiosulfate utilization sulfurtransferase TsuB/YeeD | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | D3GZ85 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9LNR0 |