Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
Location | 3701112..3701653 | Replicon | chromosome |
Accession | NZ_CP103544 | ||
Organism | Escherichia coli strain 3036 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | U9XPG0 |
Locus tag | M5S54_RS17980 | Protein ID | WP_000615976.1 |
Coordinates | 3701375..3701653 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | S1EWQ0 |
Locus tag | M5S54_RS17975 | Protein ID | WP_000729704.1 |
Coordinates | 3701112..3701372 (+) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M5S54_RS17950 (3696895) | 3696895..3697680 | - | 786 | WP_000207575.1 | putative lateral flagellar export/assembly protein LafU | - |
M5S54_RS17955 (3697652) | 3697652..3699364 | + | 1713 | Protein_3514 | flagellar biosynthesis protein FlhA | - |
M5S54_RS17960 (3699469) | 3699469..3699747 | + | 279 | WP_000598760.1 | type II toxin-antitoxin system HicA family toxin | - |
M5S54_RS17965 (3699740) | 3699740..3700096 | + | 357 | WP_001030483.1 | type II toxin-antitoxin system HicB family antitoxin | - |
M5S54_RS17970 (3700153) | 3700153..3700926 | - | 774 | WP_000543895.1 | C40 family peptidase | - |
M5S54_RS17975 (3701112) | 3701112..3701372 | + | 261 | WP_000729704.1 | type II toxin-antitoxin system antitoxin DinJ | Antitoxin |
M5S54_RS17980 (3701375) | 3701375..3701653 | + | 279 | WP_000615976.1 | type II toxin-antitoxin system mRNA interferase toxin YafQ | Toxin |
M5S54_RS17985 (3701809) | 3701809..3702549 | + | 741 | WP_063100007.1 | peptidoglycan meso-diaminopimelic acid protein amidase | - |
M5S54_RS17990 (3702520) | 3702520..3703287 | - | 768 | WP_000333380.1 | class II glutamine amidotransferase | - |
M5S54_RS17995 (3703493) | 3703493..3704071 | - | 579 | WP_000284050.1 | D-sedoheptulose 7-phosphate isomerase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | gmhA/lpcA | 3699740..3712439 | 12699 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | U9XPG0 |
Antitoxin
Source | ID | Structure |
---|---|---|
PDB | 4ML0 | |
AlphaFold DB | A0A0E0Y6Z6 |