Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 3035942..3036591 Replicon chromosome
Accession NZ_CP103450
Organism Erwinia pyrifoliae strain CP201179

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NYP81_RS14390 Protein ID WP_259816649.1
Coordinates 3036253..3036591 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NYP81_RS14385 Protein ID WP_259817530.1
Coordinates 3035942..3036253 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP81_RS14345 (NYP81_14345) 3031412..3031882 - 471 WP_004160604.1 30S ribosomal protein S7 -
NYP81_RS14350 (NYP81_14350) 3031979..3032353 - 375 WP_003852912.1 30S ribosomal protein S12 -
NYP81_RS14355 (NYP81_14355) 3032480..3032767 - 288 WP_014539655.1 sulfurtransferase complex subunit TusB -
NYP81_RS14360 (NYP81_14360) 3032775..3033134 - 360 WP_014539656.1 sulfurtransferase complex subunit TusC -
NYP81_RS14365 (NYP81_14365) 3033134..3033520 - 387 WP_259816654.1 sulfurtransferase complex subunit TusD -
NYP81_RS14370 (NYP81_14370) 3033520..3034242 - 723 WP_014542602.1 transcriptional regulator -
NYP81_RS14375 (NYP81_14375) 3034447..3035283 - 837 WP_259816653.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
NYP81_RS14380 (NYP81_14380) 3035575..3035793 + 219 WP_015899099.1 SlyX family protein -
NYP81_RS14385 (NYP81_14385) 3035942..3036253 - 312 WP_259817530.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NYP81_RS14390 (NYP81_14390) 3036253..3036591 - 339 WP_259816649.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYP81_RS14395 (NYP81_14395) 3037142..3037684 - 543 WP_014539661.1 peptidylprolyl isomerase -
NYP81_RS14400 (NYP81_14400) 3037824..3038018 - 195 WP_014539662.1 YheV family putative zinc ribbon protein -
NYP81_RS14405 (NYP81_14405) 3038075..3039880 - 1806 WP_014539663.1 glutathione-regulated potassium-efflux system protein KefB -
NYP81_RS14410 (NYP81_14410) 3039881..3040432 - 552 WP_014539664.1 glutathione-regulated potassium-efflux system ancillary protein KefG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(44-87)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13653.66 Da        Isoelectric Point: 9.9741

>T255065 WP_259816649.1 NZ_CP103450:c3036591-3036253 [Erwinia pyrifoliae]
MEALFVELPPFERYRAEYLNDDEFREFQQQLLKNPLCGDVIQKTGGLRKVRFADSRRNKGKRGGIRVIYYWYLEKSHFLL
FTLYDKDQKDDLTTTQREQLREMLEQAKKRRK

Download         Length: 339 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11590.41 Da        Isoelectric Point: 10.3434

>AT255065 WP_259817530.1 NZ_CP103450:c3036253-3035942 [Erwinia pyrifoliae]
MTKRDIFAELNEGMEAWGEFNAGQKTLRTHRASFKPASMTPAEVKAVREKLKLSQAVFAQYLHTGVTTLQNWEQGLARPN
KQAVLLIKMVDKNPQTLHELAAL

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References