Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3709328..3709980 Replicon chromosome
Accession NZ_CP103401
Organism Pantoea agglomerans strain CHTF15

Toxin (Protein)


Gene name higB Uniprot ID A0A8X8DRT2
Locus tag NYF24_RS17410 Protein ID WP_010672045.1
Coordinates 3709328..3709681 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A8X8DRN0
Locus tag NYF24_RS17415 Protein ID WP_010252120.1
Coordinates 3709681..3709980 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF24_RS17395 (3705054) 3705054..3706838 - 1785 WP_060681540.1 GMC family oxidoreductase -
NYF24_RS17400 (3706841) 3706841..3707575 - 735 WP_010672043.1 gluconate 2-dehydrogenase subunit 3 family protein -
NYF24_RS17405 (3707852) 3707852..3709093 + 1242 WP_010672044.1 peptide antibiotic transporter SbmA -
NYF24_RS17410 (3709328) 3709328..3709681 + 354 WP_010672045.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYF24_RS17415 (3709681) 3709681..3709980 + 300 WP_010252120.1 XRE family transcriptional regulator Antitoxin
NYF24_RS17420 (3710102) 3710102..3711154 - 1053 WP_061901847.1 YncE family protein -
NYF24_RS17425 (3711357) 3711357..3711566 - 210 WP_009092571.1 DUF1471 domain-containing protein -
NYF24_RS17430 (3711779) 3711779..3712966 - 1188 WP_258993052.1 MFS transporter -
NYF24_RS17435 (3713071) 3713071..3714036 + 966 WP_033770846.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13660.67 Da        Isoelectric Point: 7.9792

>T255002 WP_010672045.1 NZ_CP103401:3709328-3709681 [Pantoea agglomerans]
MWTVLLSPRFESWLSEQEEALQEKMLADLGKLKVYGPDLPRPYADTLKGSQYRNMKELRVQFSGKPIRAFYAFDPVRQAI
VLCAGDKSHDKRFYIRMIRIADDEFSAWLAEQEKGNN

Download         Length: 354 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11116.99 Da        Isoelectric Point: 6.3781

>AT255002 WP_010252120.1 NZ_CP103401:3709681-3709980 [Pantoea agglomerans]
MRTLDDVIADFSPESQARIKKMSDEMILEVGLQMIREELQLSQKTLAEAMGVRQPAVAQIEQRGNEIKVATLKRYVEAMG
GKLSLDVELPTGKRVAFRI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References