Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2786368..2786972 Replicon chromosome
Accession NZ_CP103401
Organism Pantoea agglomerans strain CHTF15

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NYF24_RS13050 Protein ID WP_010669712.1
Coordinates 2786368..2786679 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NYF24_RS13055 Protein ID WP_010669711.1
Coordinates 2786679..2786972 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF24_RS13030 (2781378) 2781378..2782325 - 948 WP_010254263.1 ABC transporter ATP-binding protein -
NYF24_RS13035 (2782318) 2782318..2783493 - 1176 WP_187505321.1 ABC transporter permease -
NYF24_RS13040 (2783497) 2783497..2784408 - 912 WP_022625994.1 ABC transporter substrate-binding protein -
NYF24_RS13045 (2784715) 2784715..2786190 + 1476 WP_033785500.1 MFS transporter -
NYF24_RS13050 (2786368) 2786368..2786679 + 312 WP_010669712.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYF24_RS13055 (2786679) 2786679..2786972 + 294 WP_010669711.1 NadS family protein Antitoxin
NYF24_RS13060 (2787109) 2787109..2787651 - 543 WP_050679469.1 isopentenyl-diphosphate Delta-isomerase -
NYF24_RS13065 (2787798) 2787798..2789693 - 1896 WP_022625996.1 methyl-accepting chemotaxis protein -
NYF24_RS13070 (2789885) 2789885..2790994 - 1110 WP_022625997.1 suppressor of fused domain protein -
NYF24_RS13075 (2791325) 2791325..2791552 - 228 WP_157351749.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11997.67 Da        Isoelectric Point: 5.8988

>T254995 WP_010669712.1 NZ_CP103401:2786368-2786679 [Pantoea agglomerans]
MLFIETPVFTEDVKELLSDDEYREFQQFMADNPGWGDVIQNTGGLRKVRWAAKGKGKRGGVRVIYYYKVSESQIRLLLIY
KKGVQDDLSEDEKHLLRALNEGW

Download         Length: 312 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10741.39 Da        Isoelectric Point: 10.6798

>AT254995 WP_010669711.1 NZ_CP103401:2786679-2786972 [Pantoea agglomerans]
MDKKLFERLKESMTQMNEIVEGSRAPARESTVTAVKVKAIRNATGLSQSGFAKLISVNVDTLKNWEQGRREPTGPAKALL
RAIERDPQHVIPALADK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References