254992

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1497303..1498633 Replicon chromosome
Accession NZ_CP103401
Organism Pantoea agglomerans strain CHTF15

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag NYF24_RS06840 Protein ID WP_258995128.1
Coordinates 1497303..1498325 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag NYF24_RS06845 Protein ID WP_031591302.1
Coordinates 1498322..1498633 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF24_RS06835 (1494958) 1494958..1497177 + 2220 WP_258995126.1 catalase/peroxidase HPI -
NYF24_RS06840 (1497303) 1497303..1498325 - 1023 WP_258995128.1 HipA domain-containing protein Toxin
NYF24_RS06845 (1498322) 1498322..1498633 - 312 WP_031591302.1 HipA N-terminal domain-containing protein Antitoxin
NYF24_RS06850 (1498618) 1498618..1498962 - 345 WP_182504314.1 helix-turn-helix transcriptional regulator -
NYF24_RS06860 (1499740) 1499740..1500861 + 1122 WP_050680121.1 Gfo/Idh/MocA family oxidoreductase -
NYF24_RS06865 (1500952) 1500952..1501782 - 831 WP_010247974.1 glycosyltransferase family 8 protein -
NYF24_RS06870 (1501795) 1501795..1503177 - 1383 WP_061703798.1 D-arabinono-1,4-lactone oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38564.16 Da        Isoelectric Point: 6.8345

>T254992 WP_258995128.1 NZ_CP103401:c1498325-1497303 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLAKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPEELAFVIKRYDRTASDYARLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENDAGNAPGINSEYGEYLGADFILLAQGIDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTEI

Download         Length: 1023 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11696.49 Da        Isoelectric Point: 4.7953

>AT254992 WP_031591302.1 NZ_CP103401:c1498633-1498322 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGQNGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References