Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2094664..2094910 Replicon chromosome
Accession NZ_CP103351
Organism Bacillus subtilis strain SRCM115947

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag NX819_RS10575 Protein ID WP_109789044.1
Coordinates 2094664..2094756 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2094737..2094910 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX819_RS10560 (NX819_10560) 2089823..2090158 + 336 WP_009967409.1 hypothetical protein -
NX819_RS10565 (NX819_10565) 2090205..2093810 - 3606 WP_004399367.1 P-loop NTPase fold protein -
NX819_RS10570 (NX819_10570) 2094043..2094375 - 333 WP_026009814.1 hypothetical protein -
NX819_RS10575 (NX819_10575) 2094664..2094756 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2094737..2094910 - 174 - - Antitoxin
NX819_RS10580 (NX819_10580) 2095025..2095867 - 843 WP_003231327.1 hypothetical protein -
NX819_RS10585 (NX819_10585) 2096067..2096525 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
NX819_RS10590 (NX819_10590) 2096535..2098337 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
NX819_RS10595 (NX819_10595) 2098439..2098996 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2081059..2104327 23268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-24)


Sequences


Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T254985 WP_109789044.1 NZ_CP103351:2094664-2094756 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp


Antitoxin


Download         Length: 174 bp

>AT254985 NZ_CP103351:c2094910-2094737 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References