254899

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 5632867..5633476 Replicon chromosome
Accession NZ_CP103300
Organism Endozoicomonas euniceicola strain EF212

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NX720_RS22925 Protein ID WP_262597780.1
Coordinates 5632867..5633187 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NX720_RS22930 Protein ID WP_262567254.1
Coordinates 5633180..5633476 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX720_RS22895 (NX720_22895) 5628983..5629162 - 180 WP_262597772.1 hypothetical protein -
NX720_RS22900 (NX720_22900) 5629335..5629604 - 270 WP_262597774.1 type II toxin-antitoxin system YafQ family toxin -
NX720_RS22905 (NX720_22905) 5629604..5629867 - 264 WP_262597776.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
NX720_RS22910 (NX720_22910) 5630249..5630980 + 732 WP_262601641.1 CRISPR-associated endonuclease Cas1 -
NX720_RS22915 (NX720_22915) 5631051..5631479 - 429 WP_262595354.1 IS200/IS605 family transposase -
NX720_RS22920 (NX720_22920) 5631545..5632717 + 1173 WP_262597778.1 transposase -
NX720_RS22925 (NX720_22925) 5632867..5633187 + 321 WP_262597780.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NX720_RS22930 (NX720_22930) 5633180..5633476 + 297 WP_262567254.1 NadS family protein Antitoxin
NX720_RS22935 (NX720_22935) 5636168..5636854 - 687 WP_262597781.1 DUF1887 family CARF protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 5631051..5631479 428


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(42-74)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12264.07 Da        Isoelectric Point: 7.9397

>T254899 WP_262597780.1 NZ_CP103300:5632867-5633187 [Endozoicomonas euniceicola]
MEFVETSVFTKIITQLMSDDDYRVMQETMIAQPDIGSVIKGTGGLRKFRWKLGSSGKRGGVRTIYYWQVSEDTFYMLYAY
TKNRQIDLTSAEKKVLSELARELCNE

Download         Length: 321 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11264.98 Da        Isoelectric Point: 9.7670

>AT254899 WP_262567254.1 NZ_CP103300:5633180-5633476 [Endozoicomonas euniceicola]
MSDHEFNFDELVESVREAIDINKGIKKPSRTFQYEEIDVASIRKATHLSQEKFAALIGVSIKTVQSWEQKVRKPLGPARS
LLIMFRNNPVQAMNLLHQ

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References