Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2414642..2414826 Replicon chromosome
Accession NZ_CP102977
Organism Staphylococcus aureus strain 27-G-H

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW957_RS12005 Protein ID WP_000482647.1
Coordinates 2414719..2414826 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2414642..2414702 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW957_RS11990 2410153..2410320 - 168 WP_001790576.1 hypothetical protein -
NW957_RS11995 2410550..2412283 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
NW957_RS12000 2412308..2414071 - 1764 WP_001064814.1 ABC transporter ATP-binding protein -
- 2414642..2414702 + 61 - - Antitoxin
NW957_RS12005 2414719..2414826 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW957_RS12010 2414960..2415346 - 387 WP_000779360.1 flippase GtxA -
NW957_RS12015 2415604..2416746 + 1143 WP_165468810.1 glycerate kinase -
NW957_RS12020 2416806..2417465 + 660 WP_000831298.1 membrane protein -
NW957_RS12025 2417647..2418858 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW957_RS12030 2418981..2419454 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254789 WP_000482647.1 NZ_CP102977:c2414826-2414719 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254789 NZ_CP102977:2414642-2414702 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References