Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2123759..2123975 Replicon chromosome
Accession NZ_CP102977
Organism Staphylococcus aureus strain 27-G-H

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW957_RS10495 Protein ID WP_001802298.1
Coordinates 2123871..2123975 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2123759..2123814 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW957_RS10470 2119905..2120570 - 666 WP_001024095.1 SDR family oxidoreductase -
NW957_RS10475 2120722..2121042 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW957_RS10480 2121044..2122024 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW957_RS10485 2122290..2123381 + 1092 WP_000495671.1 lytic regulatory protein -
- 2123759..2123814 + 56 - - Antitoxin
NW957_RS10495 2123871..2123975 - 105 WP_001802298.1 hypothetical protein Toxin
NW957_RS10500 2124073..2124580 - 508 Protein_2025 recombinase family protein -
NW957_RS10505 2124680..2125816 - 1137 WP_165468711.1 SAP domain-containing protein -
NW957_RS10515 2126873..2127730 - 858 WP_072496945.1 HAD family hydrolase -
NW957_RS10520 2127798..2128580 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254786 WP_001802298.1 NZ_CP102977:c2123975-2123871 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT254786 NZ_CP102977:2123759-2123814 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References