Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2476243..2476766 Replicon chromosome
Accession NZ_CP102975
Organism Staphylococcus aureus strain 16CS0209

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NW953_RS12185 Protein ID WP_124780700.1
Coordinates 2476243..2476509 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NW953_RS12190 Protein ID WP_000587622.1
Coordinates 2476509..2476766 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW953_RS12165 (NW953_12165) 2471456..2472643 - 1188 WP_000026189.1 MFS transporter -
NW953_RS12170 (NW953_12170) 2473038..2473814 - 777 WP_000072151.1 iron export ABC transporter permease subunit FetB -
NW953_RS12175 (NW953_12175) 2473807..2474469 - 663 WP_258409397.1 ATP-binding cassette domain-containing protein -
NW953_RS12180 (NW953_12180) 2474821..2475897 - 1077 WP_258409398.1 M42 family metallopeptidase -
NW953_RS12185 (NW953_12185) 2476243..2476509 - 267 WP_124780700.1 Txe/YoeB family addiction module toxin Toxin
NW953_RS12190 (NW953_12190) 2476509..2476766 - 258 WP_000587622.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NW953_RS12195 (NW953_12195) 2477125..2477580 + 456 WP_000732090.1 YehR family lipoprotein -
NW953_RS12200 (NW953_12200) 2477748..2479325 - 1578 WP_258409399.1 FMN-binding glutamate synthase family protein -
NW953_RS12205 (NW953_12205) 2479520..2480269 + 750 WP_000072452.1 CPBP family lipoprotein N-acylation protein LnsB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10668.35 Da        Isoelectric Point: 10.1384

>T254777 WP_124780700.1 NZ_CP102975:c2476509-2476243 [Staphylococcus aureus]
MSNYTVKIKNSAKLDLKKIKHPYLKKTFIEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYAVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9814.82 Da        Isoelectric Point: 4.3304

>AT254777 WP_000587622.1 NZ_CP102975:c2476766-2476509 [Staphylococcus aureus]
MIITSPTEARKHFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETMYLESTGTMDKVREREKDNSGTTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References