Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2443162..2443346 Replicon chromosome
Accession NZ_CP102975
Organism Staphylococcus aureus strain 16CS0209

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag NW953_RS12040 Protein ID WP_047527328.1
Coordinates 2443239..2443346 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2443162..2443222 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW953_RS12015 (NW953_12015) 2438706..2439821 - 1116 WP_258410005.1 pyridoxal phosphate-dependent aminotransferase family protein -
NW953_RS12020 (NW953_12020) 2439799..2440806 - 1008 WP_258409385.1 biotin synthase BioB -
NW953_RS12025 (NW953_12025) 2440808..2442166 - 1359 WP_234746880.1 adenosylmethionine--8-amino-7-oxononanoate transaminase -
NW953_RS12030 (NW953_12030) 2442144..2442830 - 687 WP_258409386.1 dethiobiotin synthase -
NW953_RS12035 (NW953_12035) 2442885..2443052 - 168 WP_258409387.1 hypothetical protein -
- 2443162..2443222 + 61 - - Antitoxin
NW953_RS12040 (NW953_12040) 2443239..2443346 - 108 WP_047527328.1 type I toxin-antitoxin system Fst family toxin Toxin
NW953_RS12045 (NW953_12045) 2443480..2443866 - 387 WP_000779353.1 flippase GtxA -
NW953_RS12050 (NW953_12050) 2444134..2445276 + 1143 WP_258409388.1 glycerate kinase -
NW953_RS12055 (NW953_12055) 2445336..2445995 + 660 WP_258409389.1 hypothetical protein -
NW953_RS12060 (NW953_12060) 2446175..2447386 + 1212 WP_258409390.1 multidrug effflux MFS transporter -
NW953_RS12065 (NW953_12065) 2447509..2447982 - 474 WP_258409391.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254776 WP_047527328.1 NZ_CP102975:c2443346-2443239 [Staphylococcus aureus]
MFNLLIDIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254776 NZ_CP102975:2443162-2443222 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References