Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2421897..2422414 Replicon chromosome
Accession NZ_CP102975
Organism Staphylococcus aureus strain 16CS0209

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NW953_RS11915 Protein ID WP_258409379.1
Coordinates 2421897..2422163 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NW953_RS11920 Protein ID WP_089535274.1
Coordinates 2422163..2422414 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW953_RS11885 (NW953_11885) 2417103..2417639 - 537 WP_070004150.1 GNAT family N-acetyltransferase -
NW953_RS11890 (NW953_11890) 2418107..2418931 - 825 WP_000594640.1 formate/nitrite transporter family protein -
NW953_RS11895 (NW953_11895) 2419134..2419316 - 183 WP_000079140.1 hypothetical protein -
NW953_RS11900 (NW953_11900) 2419403..2419870 - 468 WP_258409378.1 SRPBCC domain-containing protein -
NW953_RS11905 (NW953_11905) 2420056..2421603 - 1548 WP_000727756.1 zinc ABC transporter substrate-binding lipoprotein AdcA -
NW953_RS11910 (NW953_11910) 2421791..2421862 - 72 WP_234697003.1 hypothetical protein -
NW953_RS11915 (NW953_11915) 2421897..2422163 - 267 WP_258409379.1 Txe/YoeB family addiction module toxin Toxin
NW953_RS11920 (NW953_11920) 2422163..2422414 - 252 WP_089535274.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NW953_RS11925 (NW953_11925) 2422578..2422679 - 102 Protein_2301 hypothetical protein -
NW953_RS11930 (NW953_11930) 2422686..2423285 - 600 WP_070974178.1 DsbA family protein -
NW953_RS11935 (NW953_11935) 2423304..2423666 - 363 WP_000819845.1 DUF4467 domain-containing protein -
NW953_RS11940 (NW953_11940) 2423921..2425171 + 1251 WP_001012237.1 FemA/FemB family glycyltransferase FmhA -
NW953_RS11945 (NW953_11945) 2425268..2425999 - 732 WP_123097786.1 amino acid ABC transporter ATP-binding protein -
NW953_RS11950 (NW953_11950) 2425996..2426715 - 720 WP_000479573.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10495.99 Da        Isoelectric Point: 10.1856

>T254775 WP_258409379.1 NZ_CP102975:c2422163-2421897 [Staphylococcus aureus]
MARLNITFSPQAFEDYKYFQQNDKKMVNKINELLKSIDRNGTLKGRGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9420.60 Da        Isoelectric Point: 4.3407

>AT254775 WP_089535274.1 NZ_CP102975:c2422414-2422163 [Staphylococcus aureus]
MIIKTYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References