Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2157141..2157404 Replicon chromosome
Accession NZ_CP102975
Organism Staphylococcus aureus strain 16CS0209

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag NW953_RS10535 Protein ID WP_075583739.1
Coordinates 2157300..2157404 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2157141..2157305 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW953_RS10515 (NW953_10515) 2153318..2153983 - 666 WP_001024095.1 SDR family oxidoreductase -
NW953_RS10520 (NW953_10520) 2154135..2154455 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW953_RS10525 (NW953_10525) 2154457..2155437 + 981 WP_123097712.1 CDF family zinc efflux transporter CzrB -
NW953_RS10530 (NW953_10530) 2155703..2156794 + 1092 WP_258409314.1 transcriptional regulator -
- 2157141..2157305 + 165 - - Antitoxin
NW953_RS10535 (NW953_10535) 2157300..2157404 - 105 WP_075583739.1 hypothetical protein Toxin
NW953_RS13540 2157565..2157663 - 99 Protein_2032 resolvase -
NW953_RS10540 (NW953_10540) 2158081..2158239 + 159 WP_024928151.1 hypothetical protein -
NW953_RS10545 (NW953_10545) 2158686..2158778 + 93 WP_000142674.1 hypothetical protein -
NW953_RS10550 (NW953_10550) 2158899..2159756 - 858 WP_072512359.1 HAD family hydrolase -
NW953_RS10555 (NW953_10555) 2159824..2160606 - 783 WP_258409315.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T254774 WP_075583739.1 NZ_CP102975:c2157404-2157300 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT254774 NZ_CP102975:2157141-2157305 [Staphylococcus aureus]
GTAGTAAGTAGAAGTAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGTCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References