Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2428919..2429103 Replicon chromosome
Accession NZ_CP102974
Organism Staphylococcus aureus strain 01-RR-86

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW945_RS11970 Protein ID WP_000482647.1
Coordinates 2428996..2429103 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2428919..2428979 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW945_RS11955 (NW945_11955) 2424373..2424540 - 168 WP_001790576.1 hypothetical protein -
NW945_RS11960 (NW945_11960) 2424771..2426504 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
NW945_RS11965 (NW945_11965) 2426529..2428292 - 1764 WP_001064835.1 ATP-binding cassette domain-containing protein -
- 2428919..2428979 + 61 - - Antitoxin
NW945_RS11970 (NW945_11970) 2428996..2429103 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW945_RS11975 (NW945_11975) 2429237..2429623 - 387 WP_000779360.1 flippase GtxA -
NW945_RS11980 (NW945_11980) 2429881..2431023 + 1143 WP_001176863.1 glycerate kinase -
NW945_RS11985 (NW945_11985) 2431083..2431742 + 660 WP_000831298.1 membrane protein -
NW945_RS11990 (NW945_11990) 2431924..2433135 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW945_RS11995 (NW945_11995) 2433258..2433731 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254765 WP_000482647.1 NZ_CP102974:c2429103-2428996 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254765 NZ_CP102974:2428919-2428979 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References