Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2123603..2123865 Replicon chromosome
Accession NZ_CP102974
Organism Staphylococcus aureus strain 01-RR-86

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag NW945_RS10375 Protein ID WP_258414267.1
Coordinates 2123761..2123865 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2123603..2123766 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW945_RS10355 (NW945_10355) 2119786..2120451 - 666 WP_001024095.1 SDR family oxidoreductase -
NW945_RS10360 (NW945_10360) 2120603..2120923 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW945_RS10365 (NW945_10365) 2120925..2121905 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
NW945_RS10370 (NW945_10370) 2122171..2123262 + 1092 WP_000495682.1 hypothetical protein -
- 2123603..2123766 + 164 - - Antitoxin
NW945_RS10375 (NW945_10375) 2123761..2123865 - 105 WP_258414267.1 hypothetical protein Toxin
NW945_RS10380 (NW945_10380) 2124382..2124552 + 171 WP_001792292.1 transposase -
NW945_RS10385 (NW945_10385) 2124545..2124703 + 159 WP_001792784.1 hypothetical protein -
NW945_RS10390 (NW945_10390) 2125362..2126219 - 858 WP_000370931.1 HAD family hydrolase -
NW945_RS10395 (NW945_10395) 2126287..2127069 - 783 WP_258414268.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3897.76 Da        Isoelectric Point: 4.5441

>T254762 WP_258414267.1 NZ_CP102974:c2123865-2123761 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDQKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT254762 NZ_CP102974:2123603-2123766 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAGAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References