254755

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2506368..2506552 Replicon chromosome
Accession NZ_CP102972
Organism Staphylococcus aureus strain 05-RR-90

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW963_RS12565 Protein ID WP_000482647.1
Coordinates 2506445..2506552 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2506368..2506428 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW963_RS12555 (NW963_12550) 2502296..2504029 - 1734 WP_258410232.1 ABC transporter ATP-binding protein -
NW963_RS12560 (NW963_12555) 2504054..2505817 - 1764 WP_001064814.1 ABC transporter ATP-binding protein -
- 2506368..2506428 + 61 - - Antitoxin
NW963_RS12565 (NW963_12560) 2506445..2506552 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW963_RS12570 (NW963_12565) 2506686..2507072 - 387 WP_000779347.1 flippase GtxA -
NW963_RS12575 (NW963_12570) 2507330..2508472 + 1143 WP_001176863.1 glycerate kinase -
NW963_RS12580 (NW963_12575) 2508532..2509191 + 660 WP_000831298.1 membrane protein -
NW963_RS12585 (NW963_12580) 2509373..2510584 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW963_RS12590 (NW963_12585) 2510707..2511180 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2500302..2501948 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254755 WP_000482647.1 NZ_CP102972:c2506552-2506445 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254755 NZ_CP102972:2506368-2506428 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References