254753

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2173627..2173889 Replicon chromosome
Accession NZ_CP102972
Organism Staphylococcus aureus strain 05-RR-90

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW963_RS10755 Protein ID WP_001802298.1
Coordinates 2173785..2173889 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2173627..2173790 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW963_RS10730 (NW963_10725) 2169867..2170532 - 666 WP_001024095.1 SDR family oxidoreductase -
NW963_RS10735 (NW963_10730) 2170684..2171004 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW963_RS10740 (NW963_10735) 2171006..2171986 + 981 WP_258412249.1 CDF family zinc efflux transporter CzrB -
NW963_RS10745 (NW963_10740) 2172252..2173343 + 1092 WP_258412250.1 transcriptional regulator -
- 2173627..2173790 + 164 - - Antitoxin
NW963_RS10755 (NW963_10750) 2173785..2173889 - 105 WP_001802298.1 hypothetical protein Toxin
NW963_RS10760 (NW963_10755) 2174406..2174576 + 171 WP_001792292.1 transposase -
NW963_RS10765 (NW963_10760) 2174569..2174727 + 159 WP_001792784.1 hypothetical protein -
NW963_RS10770 (NW963_10765) 2175385..2176242 - 858 WP_258412251.1 HAD family hydrolase -
NW963_RS10775 (NW963_10770) 2176310..2177092 - 783 WP_258412252.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254753 WP_001802298.1 NZ_CP102972:c2173889-2173785 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT254753 NZ_CP102972:2173627-2173790 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAACCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References