Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2426128..2426312 Replicon chromosome
Accession NZ_CP102971
Organism Staphylococcus aureus strain 08-G-E

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag NW975_RS11955 Protein ID WP_000482650.1
Coordinates 2426205..2426312 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2426128..2426188 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW975_RS11940 (NW975_11940) 2421582..2421749 - 168 WP_258414742.1 hypothetical protein -
NW975_RS11945 (NW975_11945) 2421980..2423713 - 1734 WP_049307645.1 ABC transporter ATP-binding protein -
NW975_RS11950 (NW975_11950) 2423738..2425501 - 1764 WP_001064837.1 ABC transporter ATP-binding protein -
- 2426128..2426188 + 61 - - Antitoxin
NW975_RS11955 (NW975_11955) 2426205..2426312 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
NW975_RS11960 (NW975_11960) 2426446..2426832 - 387 WP_000779358.1 flippase GtxA -
NW975_RS11965 (NW975_11965) 2427100..2428242 + 1143 WP_001176863.1 glycerate kinase -
NW975_RS11970 (NW975_11970) 2428302..2428961 + 660 WP_000831298.1 membrane protein -
NW975_RS11975 (NW975_11975) 2429143..2430354 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW975_RS11980 (NW975_11980) 2430477..2430950 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T254745 WP_000482650.1 NZ_CP102971:c2426312-2426205 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254745 NZ_CP102971:2426128-2426188 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References