Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2132855..2133052 Replicon chromosome
Accession NZ_CP102971
Organism Staphylococcus aureus strain 08-G-E

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW975_RS10445 Protein ID WP_001802298.1
Coordinates 2132948..2133052 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2132855..2132893 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW975_RS10420 (NW975_10420) 2128973..2129638 - 666 WP_001024095.1 SDR family oxidoreductase -
NW975_RS10425 (NW975_10425) 2129790..2130110 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW975_RS10430 (NW975_10430) 2130112..2131092 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW975_RS10435 (NW975_10435) 2131358..2132449 + 1092 WP_258412250.1 transcriptional regulator -
NW975_RS10440 (NW975_10440) 2132835..2132909 + 75 Protein_2013 hypothetical protein -
- 2132855..2132893 + 39 - - Antitoxin
NW975_RS10445 (NW975_10445) 2132948..2133052 - 105 WP_001802298.1 hypothetical protein Toxin
NW975_RS10450 (NW975_10450) 2133732..2133890 + 159 WP_001792784.1 hypothetical protein -
NW975_RS10455 (NW975_10455) 2134548..2135405 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NW975_RS10460 (NW975_10460) 2135473..2136255 - 783 WP_258412620.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254743 WP_001802298.1 NZ_CP102971:c2133052-2132948 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254743 NZ_CP102971:2132855-2132893 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References