Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2131906..2132104 Replicon chromosome
Accession NZ_CP102970
Organism Staphylococcus aureus strain 09-G-F

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag NW983_RS10455 Protein ID WP_075583739.1
Coordinates 2132000..2132104 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2131906..2131944 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW983_RS10430 (NW983_10430) 2128021..2128686 - 666 WP_001024095.1 SDR family oxidoreductase -
NW983_RS10435 (NW983_10435) 2128838..2129158 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW983_RS10440 (NW983_10440) 2129160..2130137 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
NW983_RS10445 (NW983_10445) 2130403..2131494 + 1092 WP_061838836.1 hypothetical protein -
NW983_RS10450 (NW983_10450) 2131886..2131960 + 75 Protein_2015 hypothetical protein -
- 2131906..2131944 + 39 - - Antitoxin
NW983_RS10455 (NW983_10455) 2132000..2132104 - 105 WP_075583739.1 hypothetical protein Toxin
NW983_RS10460 (NW983_10460) 2132202..2132363 - 162 Protein_2017 helix-turn-helix domain-containing protein -
NW983_RS10465 (NW983_10465) 2132781..2132939 + 159 WP_024928151.1 hypothetical protein -
NW983_RS10470 (NW983_10470) 2133387..2133479 + 93 WP_000142674.1 hypothetical protein -
NW983_RS10475 (NW983_10475) 2133600..2134457 - 858 WP_000370921.1 HAD family hydrolase -
NW983_RS10480 (NW983_10480) 2134525..2135307 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T254732 WP_075583739.1 NZ_CP102970:c2132104-2132000 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp


Antitoxin


Download         Length: 39 bp

>AT254732 NZ_CP102970:2131906-2131944 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References