Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2107247..2107444 Replicon chromosome
Accession NZ_CP102968
Organism Staphylococcus aureus strain 13-G-52

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW965_RS10245 Protein ID WP_001802298.1
Coordinates 2107340..2107444 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2107247..2107285 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW965_RS10220 (NW965_10220) 2103299..2103964 - 666 WP_001024094.1 SDR family oxidoreductase -
NW965_RS10225 (NW965_10225) 2104116..2104436 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW965_RS10230 (NW965_10230) 2104438..2105418 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW965_RS10235 (NW965_10235) 2105684..2106775 + 1092 WP_258412250.1 transcriptional regulator -
NW965_RS10240 (NW965_10240) 2107227..2107301 + 75 Protein_1973 hypothetical protein -
- 2107247..2107285 + 39 - - Antitoxin
NW965_RS10245 (NW965_10245) 2107340..2107444 - 105 WP_001802298.1 hypothetical protein Toxin
NW965_RS10250 2107961..2108131 + 171 WP_001792292.1 transposase -
NW965_RS10255 (NW965_10250) 2108124..2108282 + 159 WP_258415910.1 integrase -
NW965_RS10260 (NW965_10255) 2108940..2109797 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NW965_RS10265 (NW965_10260) 2109865..2110647 - 783 WP_162647195.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254723 WP_001802298.1 NZ_CP102968:c2107444-2107340 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254723 NZ_CP102968:2107247-2107285 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References