254707

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2145838..2146035 Replicon chromosome
Accession NZ_CP102966
Organism Staphylococcus aureus strain 29-P-01

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW955_RS10565 Protein ID WP_001802298.1
Coordinates 2145931..2146035 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2145838..2145876 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW955_RS10540 (NW955_10540) 2141956..2142621 - 666 WP_001024095.1 SDR family oxidoreductase -
NW955_RS10545 (NW955_10545) 2142773..2143093 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW955_RS10550 (NW955_10550) 2143095..2144075 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW955_RS10555 (NW955_10555) 2144341..2145432 + 1092 WP_258412250.1 transcriptional regulator -
NW955_RS10560 (NW955_10560) 2145818..2145892 + 75 Protein_2037 hypothetical protein -
- 2145838..2145876 + 39 - - Antitoxin
NW955_RS10565 (NW955_10565) 2145931..2146035 - 105 WP_001802298.1 hypothetical protein Toxin
NW955_RS10570 (NW955_10570) 2146552..2146722 + 171 WP_001792292.1 transposase -
NW955_RS10575 (NW955_10575) 2146715..2146873 + 159 WP_001792784.1 hypothetical protein -
NW955_RS10580 (NW955_10580) 2147531..2148388 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NW955_RS10585 (NW955_10585) 2148456..2149238 - 783 WP_258412620.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254707 WP_001802298.1 NZ_CP102966:c2146035-2145931 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254707 NZ_CP102966:2145838-2145876 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References