Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2513334..2513518 Replicon chromosome
Accession NZ_CP102962
Organism Staphylococcus aureus strain 16CS0212

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW971_RS12610 Protein ID WP_000482647.1
Coordinates 2513411..2513518 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2513334..2513394 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW971_RS12595 (NW971_12595) 2508788..2508955 - 168 WP_001789205.1 hypothetical protein -
NW971_RS12600 (NW971_12600) 2509186..2510919 - 1734 WP_258464492.1 ABC transporter ATP-binding protein -
NW971_RS12605 (NW971_12605) 2510944..2512707 - 1764 WP_258464493.1 ABC transporter ATP-binding protein -
- 2513334..2513394 + 61 - - Antitoxin
NW971_RS12610 (NW971_12610) 2513411..2513518 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW971_RS12615 (NW971_12615) 2513652..2514038 - 387 WP_000779353.1 flippase GtxA -
NW971_RS12620 (NW971_12620) 2514306..2515448 + 1143 WP_001176863.1 glycerate kinase -
NW971_RS12625 (NW971_12625) 2515508..2516167 + 660 WP_000831304.1 hypothetical protein -
NW971_RS12630 (NW971_12630) 2516350..2517561 + 1212 WP_258464494.1 multidrug effflux MFS transporter -
NW971_RS12635 (NW971_12635) 2517684..2518157 - 474 WP_258464495.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254687 WP_000482647.1 NZ_CP102962:c2513518-2513411 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254687 NZ_CP102962:2513334-2513394 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References