Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2213622..2213820 Replicon chromosome
Accession NZ_CP102962
Organism Staphylococcus aureus strain 16CS0212

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW971_RS11045 Protein ID WP_001802298.1
Coordinates 2213716..2213820 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2213622..2213660 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW971_RS11025 (NW971_11025) 2209593..2210258 - 666 WP_001024100.1 SDR family oxidoreductase -
NW971_RS11030 (NW971_11030) 2210410..2210730 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW971_RS11035 (NW971_11035) 2210732..2211709 + 978 WP_000019731.1 CDF family zinc efflux transporter CzrB -
NW971_RS11040 (NW971_11040) 2211975..2213066 + 1092 WP_000495691.1 hypothetical protein -
- 2213622..2213660 + 39 - - Antitoxin
NW971_RS11045 (NW971_11045) 2213716..2213820 - 105 WP_001802298.1 hypothetical protein Toxin
NW971_RS11050 (NW971_11050) 2213981..2214464 - 484 Protein_2136 recombinase family protein -
NW971_RS11055 (NW971_11055) 2214507..2215642 - 1136 Protein_2137 SAP domain-containing protein -
NW971_RS11065 (NW971_11065) 2216691..2217548 - 858 WP_258464431.1 HAD family hydrolase -
NW971_RS11070 (NW971_11070) 2217615..2218397 - 783 WP_258464432.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254685 WP_001802298.1 NZ_CP102962:c2213820-2213716 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254685 NZ_CP102962:2213622-2213660 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References