Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1920264..1920444 Replicon chromosome
Accession NZ_CP102962
Organism Staphylococcus aureus strain 16CS0212

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag NW971_RS09415 Protein ID WP_001801861.1
Coordinates 1920264..1920359 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1920387..1920444 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW971_RS09370 (NW971_09370) 1916206..1916832 + 627 WP_258464341.1 hypothetical protein -
NW971_RS09375 (NW971_09375) 1916873..1917214 + 342 WP_258464342.1 DUF3969 family protein -
NW971_RS09380 (NW971_09380) 1917315..1917887 + 573 WP_258464343.1 hypothetical protein -
NW971_RS09385 (NW971_09385) 1918085..1918567 - 483 Protein_1846 ImmA/IrrE family metallo-endopeptidase -
NW971_RS09390 (NW971_09390) 1918681..1918866 - 186 WP_111762421.1 hypothetical protein -
NW971_RS09395 (NW971_09395) 1918868..1919044 - 177 WP_000375478.1 hypothetical protein -
NW971_RS09400 (NW971_09400) 1919064..1919434 - 371 Protein_1849 hypothetical protein -
NW971_RS09405 (NW971_09405) 1919536..1919841 - 306 WP_258464344.1 IS3 family transposase -
NW971_RS09410 (NW971_09410) 1919961..1920119 - 159 WP_258464345.1 hypothetical protein -
NW971_RS09415 (NW971_09415) 1920264..1920359 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1920387..1920444 - 58 - - Antitoxin
NW971_RS09420 (NW971_09420) 1920482..1920577 + 96 Protein_1853 hypothetical protein -
NW971_RS09425 (NW971_09425) 1920600..1920731 + 132 WP_258464346.1 hypothetical protein -
NW971_RS09430 (NW971_09430) 1921286..1921729 - 444 WP_258464347.1 DUF1433 domain-containing protein -
NW971_RS09435 (NW971_09435) 1921729..1922172 - 444 WP_258464348.1 DUF1433 domain-containing protein -
NW971_RS09440 (NW971_09440) 1922697..1925117 + 2421 WP_258464349.1 polysaccharide lyase 8 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T254680 WP_001801861.1 NZ_CP102962:1920264-1920359 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T254680 NZ_CP102962:1920264-1920359 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT254680 NZ_CP102962:c1920444-1920387 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References