254673

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2483632..2483816 Replicon chromosome
Accession NZ_CP102961
Organism Staphylococcus aureus strain 03-RR-88

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW973_RS12375 Protein ID WP_000482647.1
Coordinates 2483709..2483816 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2483632..2483692 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW973_RS12360 (NW973_12360) 2479088..2479255 - 168 WP_001790576.1 hypothetical protein -
NW973_RS12365 (NW973_12365) 2479486..2481219 - 1734 WP_258410821.1 ABC transporter ATP-binding protein -
NW973_RS12370 (NW973_12370) 2481244..2483007 - 1764 WP_258410822.1 ABC transporter ATP-binding protein -
- 2483632..2483692 + 61 - - Antitoxin
NW973_RS12375 (NW973_12375) 2483709..2483816 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW973_RS12380 (NW973_12380) 2483950..2484336 - 387 WP_258410823.1 flippase GtxA -
NW973_RS12385 (NW973_12385) 2484594..2485736 + 1143 WP_001176863.1 glycerate kinase -
NW973_RS12390 (NW973_12390) 2485796..2486455 + 660 WP_258410824.1 hypothetical protein -
NW973_RS12395 (NW973_12395) 2486638..2487849 + 1212 WP_001191923.1 multidrug effflux MFS transporter -
NW973_RS12400 (NW973_12400) 2487972..2488445 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254673 WP_000482647.1 NZ_CP102961:c2483816-2483709 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254673 NZ_CP102961:2483632-2483692 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References