254671

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2195940..2196137 Replicon chromosome
Accession NZ_CP102961
Organism Staphylococcus aureus strain 03-RR-88

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW973_RS10870 Protein ID WP_001802298.1
Coordinates 2196033..2196137 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2195940..2195978 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW973_RS10845 (NW973_10845) 2192115..2192780 - 666 WP_001024095.1 SDR family oxidoreductase -
NW973_RS10850 (NW973_10850) 2192932..2193252 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW973_RS10855 (NW973_10855) 2193254..2194234 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW973_RS10860 (NW973_10860) 2194500..2195591 + 1092 WP_000495669.1 hypothetical protein -
NW973_RS10865 (NW973_10865) 2195920..2195994 + 75 Protein_2098 hypothetical protein -
- 2195940..2195978 + 39 - - Antitoxin
NW973_RS10870 (NW973_10870) 2196033..2196137 - 105 WP_001802298.1 hypothetical protein Toxin
NW973_RS10875 (NW973_10875) 2196654..2196824 + 171 WP_001792292.1 transposase -
NW973_RS10880 (NW973_10880) 2196817..2196975 + 159 WP_258410147.1 integrase -
NW973_RS10885 (NW973_10885) 2197634..2198491 - 858 WP_000370945.1 HAD family hydrolase -
NW973_RS10890 (NW973_10890) 2198559..2199341 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254671 WP_001802298.1 NZ_CP102961:c2196137-2196033 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254671 NZ_CP102961:2195940-2195978 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References