Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2453312..2453496 Replicon chromosome
Accession NZ_CP102960
Organism Staphylococcus aureus strain 07-G-D

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW949_RS12165 Protein ID WP_000482647.1
Coordinates 2453389..2453496 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2453312..2453372 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW949_RS12150 (NW949_12150) 2448842..2449009 - 168 WP_031860495.1 hypothetical protein -
NW949_RS12155 (NW949_12155) 2449240..2450973 - 1734 WP_258410232.1 ABC transporter ATP-binding protein -
NW949_RS12160 (NW949_12160) 2450998..2452761 - 1764 WP_001064814.1 ABC transporter ATP-binding protein -
- 2453312..2453372 + 61 - - Antitoxin
NW949_RS12165 (NW949_12165) 2453389..2453496 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW949_RS12170 (NW949_12170) 2453630..2454016 - 387 WP_000779358.1 flippase GtxA -
NW949_RS12175 (NW949_12175) 2454284..2455426 + 1143 WP_001176863.1 glycerate kinase -
NW949_RS12180 (NW949_12180) 2455486..2456145 + 660 WP_000831298.1 membrane protein -
NW949_RS12185 (NW949_12185) 2456327..2457538 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW949_RS12190 (NW949_12190) 2457661..2458134 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254664 WP_000482647.1 NZ_CP102960:c2453496-2453389 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254664 NZ_CP102960:2453312-2453372 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References