Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2092549..2092746 Replicon chromosome
Accession NZ_CP102958
Organism Staphylococcus aureus strain 15-G-54

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW969_RS10115 Protein ID WP_001802298.1
Coordinates 2092642..2092746 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2092549..2092587 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW969_RS10090 (NW969_10090) 2088667..2089332 - 666 WP_001024095.1 SDR family oxidoreductase -
NW969_RS10095 (NW969_10095) 2089484..2089804 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW969_RS10100 (NW969_10100) 2089806..2090786 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW969_RS10105 (NW969_10105) 2091052..2092143 + 1092 WP_258412250.1 transcriptional regulator -
NW969_RS10110 (NW969_10110) 2092529..2092603 + 75 Protein_1947 hypothetical protein -
- 2092549..2092587 + 39 - - Antitoxin
NW969_RS10115 (NW969_10115) 2092642..2092746 - 105 WP_001802298.1 hypothetical protein Toxin
NW969_RS10120 (NW969_10120) 2093426..2093584 + 159 WP_001792784.1 hypothetical protein -
NW969_RS10125 (NW969_10125) 2094242..2095099 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NW969_RS10130 (NW969_10130) 2095167..2095949 - 783 WP_258412620.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254646 WP_001802298.1 NZ_CP102958:c2092746-2092642 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254646 NZ_CP102958:2092549-2092587 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References