Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1793123..1793305 Replicon chromosome
Accession NZ_CP102958
Organism Staphylococcus aureus strain 15-G-54

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag NW969_RS08440 Protein ID WP_001801861.1
Coordinates 1793123..1793218 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1793246..1793305 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW969_RS08400 (NW969_08400) 1788793..1789419 + 627 WP_045177256.1 hypothetical protein -
NW969_RS08405 (NW969_08405) 1789460..1789801 + 342 WP_045177258.1 DUF3969 family protein -
NW969_RS08410 (NW969_08410) 1789902..1790474 + 573 WP_045177260.1 hypothetical protein -
NW969_RS08415 (NW969_08415) 1790672..1791300 - 629 Protein_1652 ImmA/IrrE family metallo-endopeptidase -
NW969_RS08420 (NW969_08420) 1791415..1791585 - 171 WP_169301139.1 hypothetical protein -
NW969_RS08425 (NW969_08425) 1791603..1791779 - 177 WP_000375477.1 hypothetical protein -
NW969_RS08430 (NW969_08430) 1791790..1792173 - 384 WP_000070811.1 hypothetical protein -
NW969_RS08435 (NW969_08435) 1792777..1792920 - 144 WP_001549059.1 transposase -
NW969_RS08440 (NW969_08440) 1793123..1793218 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1793246..1793305 - 60 - - Antitoxin
NW969_RS08445 (NW969_08445) 1793341..1793442 + 102 WP_001791893.1 hypothetical protein -
NW969_RS08450 (NW969_08450) 1793420..1793596 - 177 Protein_1659 transposase -
NW969_RS08455 (NW969_08455) 1793790..1794167 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T254642 WP_001801861.1 NZ_CP102958:1793123-1793218 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT254642 NZ_CP102958:c1793305-1793246 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References