Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2095956..2096153 Replicon chromosome
Accession NZ_CP102957
Organism Staphylococcus aureus strain 18-H-62

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW959_RS10210 Protein ID WP_001802298.1
Coordinates 2096049..2096153 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2095956..2095994 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW959_RS10185 (NW959_10185) 2092074..2092739 - 666 WP_001024095.1 SDR family oxidoreductase -
NW959_RS10190 (NW959_10190) 2092891..2093211 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW959_RS10195 (NW959_10195) 2093213..2094193 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW959_RS10200 (NW959_10200) 2094459..2095550 + 1092 WP_045177732.1 lytic regulatory protein -
NW959_RS10205 (NW959_10205) 2095936..2096010 + 75 Protein_1967 hypothetical protein -
- 2095956..2095994 + 39 - - Antitoxin
NW959_RS10210 (NW959_10210) 2096049..2096153 - 105 WP_001802298.1 hypothetical protein Toxin
NW959_RS10215 (NW959_10215) 2096833..2096991 + 159 WP_001792784.1 hypothetical protein -
NW959_RS10220 (NW959_10220) 2097649..2098506 - 858 WP_258472994.1 HAD family hydrolase -
NW959_RS10225 (NW959_10225) 2098574..2099356 - 783 WP_216712603.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254637 WP_001802298.1 NZ_CP102957:c2096153-2096049 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254637 NZ_CP102957:2095956-2095994 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References