Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2465092..2465276 Replicon chromosome
Accession NZ_CP102956
Organism Staphylococcus aureus strain 26-G-G

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW981_RS12195 Protein ID WP_000482647.1
Coordinates 2465169..2465276 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2465092..2465152 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW981_RS12180 (NW981_12180) 2460622..2460789 - 168 WP_031860495.1 hypothetical protein -
NW981_RS12185 (NW981_12185) 2461020..2462753 - 1734 WP_258410232.1 ABC transporter ATP-binding protein -
NW981_RS12190 (NW981_12190) 2462778..2464541 - 1764 WP_001064814.1 ABC transporter ATP-binding protein -
- 2465092..2465152 + 61 - - Antitoxin
NW981_RS12195 (NW981_12195) 2465169..2465276 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW981_RS12200 (NW981_12200) 2465410..2465796 - 387 WP_000779358.1 flippase GtxA -
NW981_RS12205 (NW981_12205) 2466064..2467206 + 1143 WP_001176863.1 glycerate kinase -
NW981_RS12210 (NW981_12210) 2467266..2467925 + 660 WP_000831298.1 membrane protein -
NW981_RS12215 (NW981_12215) 2468107..2469318 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW981_RS12220 (NW981_12220) 2469441..2469914 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254630 WP_000482647.1 NZ_CP102956:c2465276-2465169 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254630 NZ_CP102956:2465092-2465152 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References